Subject's own speech reduces reactivity of the human auditory cortex

被引：122

作者：

Numminen, J ^{[1
]}

Salmelin, R ^{[1
]}

Hari, R ^{[1
]}

机构：

[1] Helsinki Univ Technol, Brain Res Unit, Low Temp Lab, Helsinki 02015, Finland

来源：

NEUROSCIENCE LETTERS | 1999年 / 265卷 / 02期

基金：

芬兰科学院;

关键词：

auditory cortex; speech; magnetoencephalography; auditory evoked field; auditory response; source localization; human;

D O I：

10.1016/S0304-3940(99)00218-9

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Previous studies on monkeys have shown that uttering-related cortical areas exert an inhibitory effect on the auditory cortex, and cerebral blood-flow analyses on humans have revealed modulation of the activity of the auditory cortex during own speech. To study this modulation on a millisecond time scale, we recorded neuromagnetic evoked responses to short 1-kHz tones while the subjects were reading silently and aloud. The 100-ms response (M100) of the auditory cortex was delayed by 10-21 ms and its amplitude was dampened by 44-71% during reading aloud compared with reading silently. This effect was more prominent in responses to ipsilateral than contralateral tones, possibly due to a sum effect of diminished ipsilateral input to the cortex and decreased transcallosal excitation. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：119 / 122

页数：4

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