Reduced gating of middle-latency auditory evoked potentials (P50) in migraine patients: another indication of abnormal sensory processing?

被引：62

作者：

Ambrosini, A

De Pasqua, V

Afra, J

Sandor, PS

Schoenen, J

机构：

[1] CHR Citadelle, Univ Dept Neurol, B-4000 Liege, Belgium

[2] IRCCS Neuromed, Headache Clin, I-86077 Pozzilli, Isernia, Italy

[3] Natl Inst Neurosurg, H-1145 Budapest, Hungary

[4] Univ Zurich Hosp, Dept Neurol, Headache & Pain Unit, CH-8091 Zurich, Switzerland

来源：

NEUROSCIENCE LETTERS | 2001年 / 306卷 / 1-2期

关键词：

migraine; evoked potentials; auditory P50; sensory gating; cortical processing; habituation;

D O I：

10.1016/S0304-3940(01)01871-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Habituation of cortical evoked responses to repetitive stimuli is reduced in migraine between attacks. To explore another aspect of information processing, we measured auditory sensory gating. The amplitude of the P50 response to the second of two homologous stimuli was significantly less reduced in migraineurs than in healthy volunteers. This lack of auditory sensory gating may be due to a hypofunction of monoaminergic subcortico-cortical pathways, which is also supposed to cause the interictal deficit of cortical habituation to repetitive stimuli. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：132 / 134

页数：3

共 14 条

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