A facile scanometric strategy for ultrasensitive detection of protein using aptamer-initiated rolling circle amplification

被引:33
作者
Cheng, Wei [1 ,2 ]
Ding, Lin [1 ]
Chen, Yunlong [1 ]
Yan, Feng [3 ]
Ju, Huangxian [1 ,2 ]
Yin, Yibing [2 ]
机构
[1] Nanjing Univ, Dept Chem, Key Lab Analyt Chem Life Sci, Minist Educ China, Nanjing 210093, Peoples R China
[2] Chongqing Med Univ, Dept Key Lab Med, Lab Med Diagnost, Minist Educ China, Chongqing 400016, Peoples R China
[3] Jiangsu Inst Canc Prevent & Cure, Nanjing 210009, Peoples R China
关键词
DNA; NANOPARTICLES; MOLECULE; SENSORS; ARRAY;
D O I
10.1039/c002078h
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A pragmatic and simple strategy was developed for ultrasensitive detection of protein with good specificity and low matrix effect, which combined aptamer-initiated rolling circle amplification with a Au nanoparticle probe and convenient scanometric readout.
引用
收藏
页码:6720 / 6722
页数:3
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