Extraskeletal effects of vitamin D: Facts, uncertainties, and controversies

被引：34

作者：

Bouvard, Beatrice ^{[1
,4
]}

Annweiler, Cedric ^{[2
]}

Salle, AgneS ^{[3
]}

Beauchet, Olivier ^{[1
]}

Chappard, Daniel ^{[1
,4
]}

Audran, Maurice ^{[1
,4
]}

Legrand, Erick ^{[1
,4
]}

机构：

[1] Univ Angers, Serv Rhumatol, CHU Angers, UNAM, F-49933 Angers, France

[2] Univ Angers, Serv Gerontol Clin, CHU Angers, UNAM, F-49933 Angers, France

[3] Univ Angers, Serv Endocrinol Diabetol Nutr, CHU, UNAM, F-49933 Angers, France

[4] Univ Angers, INSERM, U922, UNAM, F-49933 Angers, France

来源：

JOINT BONE SPINE | 2011年 / 78卷 / 01期

关键词：

Vitamin D; Obesity; Cancer; Infection; Auto-immune diseases; BONE-MINERAL DENSITY; RANDOMIZED CONTROLLED-TRIALS; T-CELLS; 1,25-DIHYDROXYVITAMIN D-3; RHEUMATOID-ARTHRITIS; D SUPPLEMENTATION; BREAST-CANCER; D DEFICIENCY; SECONDARY HYPERPARATHYROIDISM; BILIOPANCREATIC DIVERSION;

D O I：

10.1016/j.jbspin.2010.10.011

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Vitamin D was long viewed as a hormone acting chiefly to regulate calcium-phosphate metabolism and bone mineralization. Over the last decade, however, basic science and clinical researchers have produced a bewildering amount of information on the extraskeletal effects of vitamin D. This article is a review of the clinical and biological actions of vitamin D including effects on the immune system, auto-immune diseases, infections, cancer, metabolic syndrome, fall risk, cognitive function, and muscle function. (C) 2010 Societe francaise de rhumatologie. Published by Elsevier Masson SAS. All rights reserved.

引用

收藏

页码：10 / 16

页数：7

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