A transcription factor party during blood cell differentiation

被引：130

作者：

Sieweke, MH ^{[1
]}

Graf, T ^{[1
]}

机构：

[1] European Mol Biol Lab, D-69117 Heidelberg, Germany

来源：

CURRENT OPINION IN GENETICS & DEVELOPMENT | 1998年 / 8卷 / 05期

关键词：

D O I：

10.1016/S0959-437X(98)80009-9

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Recent studies have shown that hematopoietic transcription factors can engage in multiple protein-protein interactions. Accumulating evidence indicates that specific complexes define differentiation lineages and differentiation stages. It is proposed that these complexes acquire new functions during blood cell differentiation through successive changes in composition - much as discussion topics of groups at a cocktail party take new directions as new people join and others leave.

引用

收藏

页码：545 / 551

页数：7

相关论文

共 58 条

[51] THE ONCOGENIC CYSTEINE-RICH LIM DOMAIN PROTEIN RBTN2 IS ESSENTIAL FOR ERYTHROID DEVELOPMENT [J].

WARREN, AJ ;

COLLEDGE, WH ;

CARLTON, MBL ;

EVANS, MJ ;

SMITH, AJH ;

RABBITTS, TH .

CELL, 1994, 78 (01) :45-57

[52] NOVEL INSIGHTS INTO ERYTHROID DEVELOPMENT REVEALED THROUGH IN-VITRO DIFFERENTIATION OF GATA-1(-) EMBRYONIC STEM-CELLS [J].

WEISS, MJ ;

KELLER, G ;

ORKIN, SH .

GENES & DEVELOPMENT, 1994, 8 (10) :1184-1197

[53] Erythroid-cell-specific properties of transcription factor GATA-1 revealed by phenotypic rescue of a gene-targeted cell line [J].

Weiss, MJ ;

Yu, CN ;

Orkin, SH .

MOLECULAR AND CELLULAR BIOLOGY, 1997, 17 (03) :1642-1651

[54] The T cell leukemia LIM protein Lmo2 is necessary for adult mouse hematopoiesis [J].

Yamada, Y ;

Warren, AJ ;

Dobson, C ;

Forster, A ;

Pannell, R ;

Rabbitts, TH .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (07) :3890-3895

[55] Impaired granulopoiesis, myelodysplasia, and early lethality in CCAAT/enhancer binding protein epsilon-deficient mice [J].

Yamanaka, R ;

Barlow, C ;

LekstromHimes, J ;

Castilla, LH ;

Liu, PP ;

Eckhaus, M ;

Decker, T ;

WynshawBoris, A ;

Xanthopoulos, KG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (24) :13187-13192

[56] A role for CREB binding protein and p300 transcriptional coactivators in Ets-1 transactivation functions [J].

Yang, C ;

Shapiro, LH ;

Rivera, M ;

Kumar, A ;

Brindle, PK .

MOLECULAR AND CELLULAR BIOLOGY, 1998, 18 (04) :2218-2229

[57] Absence of granulocyte colony-stimulating factor signaling and neutrophil development in CCAAT enhancer binding protein alpha-deficient mice [J].

Zhang, DE ;

Zhang, P ;

Wang, ND ;

Hetherington, CJ ;

Darlington, GJ ;

Tenen, DG .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (02) :569-574

[58]

Zhang DE, 1996, MOL CELL BIOL, V16, P1231

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