Synthesis of optically active diastereomers of a nonproteic neurotrophic mimetic

被引：15

作者：

KeylingBilger, F ^{[1
]}

Schmitt, G ^{[1
]}

Beck, A ^{[1
]}

Luu, B ^{[1
]}

机构：

[1] UNIV STRASBOURG 1, CTR NEUROCHIM, CNRS, LAB CHIM ORGAN SUBST NAT, F-67084 STRASBOURG, FRANCE

来源：

TETRAHEDRON | 1996年 / 52卷 / 47期

关键词：

D O I：

10.1016/0040-4020(96)00916-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The four diastereomers 3, elongated analogues of perhydroretinol, are synthesized starting from both optically pure 3-bromo-2-methyl-1-propanol enantiomers. All exhibit neurotrophic activity on cultured neuronal cells derived from fetal rat cerebral hemispheres. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：14891 / 14904

页数：14

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