The first total synthesis of veiutamine, a new type of pyrroloiminoquinone marine alkaloid

被引：22

作者：

Moro-oka, Y ^{[1
]}

Fukuda, T ^{[1
]}

Iwao, M ^{[1
]}

机构：

[1] Nagasaki Univ, Fac Engn, Dept Appl Chem, Nagasaki 8528521, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 09期

关键词：

antitumour compounds; marine metabolites; indoles; lithiation;

D O I：

10.1016/S0040-4039(99)00034-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first total synthesis of veiutamine, a new type of pyrroroiminoquinone marine alkaloid bearing a p-hydroxybenzyl substituent at C-6, has been achieved. The key step of the synthesis is 6-selective functionalization of the 1,3,4,5-tetrahydropyrrolo [4,3,2-de]quinoline nucleus via N-Boc-directed lithiation. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：1713 / 1716

页数：4

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