Can molluscs biosynthesize typical sponge metabolites? The case of the nudibranch Doriopsilla areolata

被引：20

作者：

Gavagnin, M ^{[1
]}

Mollo, E ^{[1
]}

Castelluccio, F ^{[1
]}

Ghiselin, MT ^{[1
]}

Calado, G ^{[1
]}

Cimino, G ^{[1
]}

机构：

[1] CNR, Ist Chim Mol Interesse Biol, I-80078 Pozzuoli, Na, Italy

来源：

TETRAHEDRON | 2001年 / 57卷 / 42期

关键词：

biosynthesis; molluscs; marine metabolites; terpenes and terpenoids;

D O I：

10.1016/S0040-4020(01)00876-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The first study on the biosynthesis of terpenoid metabolites in the porostome nudibranch Doriopsilla areolata is described herein. The de novo origin of two different groups of bi- and tri-cyclic sesquiterpenes, exhibiting opposite A/B ring junctions, has been clearly demonstrated by in vivo incorporation of labeled mevalonate. Surprisingly, metabolites of both series have been previously reported to co-occur in a sponge of genus Dysidea, that could be included in the diet of the nudibranch. (C) 2001 Published by Elsevier Science Ltd.

引用

页码：8913 / 8916

页数：4

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