Intravascular photoacoustic imaging of human coronary atherosclerosis

被引：224

作者：

Jansen, Krista ^{[1
]}

van der Steen, Antonius F. W. ^{[1
,3
]}

van Beusekom, Heleen M. M. ^{[1
]}

Oosterhuis, J. Wolter ^{[2
]}

van Soest, Gijs ^{[1
]}

机构：

[1] Erasmus MC, Ctr Thorax, NL-3000 CA Rotterdam, Netherlands

[2] Erasmus MC, Dept Pathol, NL-3000 CA Rotterdam, Netherlands

[3] Interuniv Cardiol Inst Netherlands, NL-3501 DG Utrecht, Netherlands

来源：

OPTICS LETTERS | 2011年 / 36卷 / 05期

关键词：

ULTRASOUND; PROGRESSION; PLAQUES; RUPTURE;

D O I：

10.1364/OL.36.000597

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

We demonstrate intravascular photoacoustic imaging of human coronary atherosclerotic plaque. The data was obtained from two fresh human coronary arteries ex vivo, showing different stages of disease. A 1.25mm diameter intravascular imaging catheter was built, comprising an angle-polished optical fiber adjacent to a 30MHz ultrasound transducer. Specific photoacoustic imaging of lipid content, a key factor in vulnerable plaques that may lead to myocardial infarction, is achieved by spectroscopic imaging at different wavelengths between 1180 and 1230 nm. Simultaneous imaging with intravascular ultrasound was performed. (C) 2011 Optical Society of America

引用

页码：597 / 599

页数：3

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