Taste and pheromone perception in mammals and flies

被引：35

作者：

Matsunami, H ^{[1
]}

Amrein, H ^{[1
]}

机构：

[1] Duke Univ, Med Ctr, Dept Mol Genet & Microbiol, Durham, NC 27710 USA

来源：

GENOME BIOLOGY | 2003年 / 4卷 / 07期

关键词：

D O I：

10.1186/gb-2003-4-7-220

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The olfactory systems of insects and mammals have analogous anatomical features and use similar molecular logic for olfactory coding. The molecular underpinnings of the chemosensory systems that detect taste and pheromone cues have only recently been characterized. Comparison of these systems in Drosophila and mouse uncovers clear differences and a few surprising similarities.

引用

页数：9

共 64 条

[1] A novel family of mammalian taste receptors [J].

Adler, E ;

Hoon, MA ;

Mueller, KL ;

Chandrashekar, J ;

Ryba, NJP ;

Zuker, CS .

CELL, 2000, 100 (06) :693-702

[2] THE MOLECULAR LOGIC OF SMELL [J].

AXEL, R .

SCIENTIFIC AMERICAN, 1995, 273 (04) :154-159

[3] Pheromone detection mediated by a V1r vomeronasal receptor [J].

Boschat, C ;

Pélofi, C ;

Randin, O ;

Roppolo, D ;

Lüscher, C ;

Broillet, MC ;

Rodriguez, I .

NATURE NEUROSCIENCE, 2002, 5 (12) :1261-1262

[4]

BRAND AH, 1993, DEVELOPMENT, V118, P401

[5] The molecular architecture of odor and pheromone sensing in mammals [J].

Buck, LB .

CELL, 2000, 100 (06) :611-618

[6] The human TAS2R16 receptor mediates bitter taste in response to β-glucopyranosides [J].

Bufe, B ;

Hofmann, T ;

Krautwurst, D ;

Raguse, JD ;

Meyerhof, W .

NATURE GENETICS, 2002, 32 (03) :397-401

[7] T2Rs function as bitter taste receptors [J].

Chandrashekar, J ;

Mueller, KL ;

Hoon, MA ;

Adler, E ;

Feng, LX ;

Guo, W ;

Zuker, CS ;

Ryba, NJP .

CELL, 2000, 100 (06) :703-711

[8] A novel family of divergent seven-transmembrane proteins:: Candidate odorant receptors in Drosophila [J].

Clyne, PJ ;

Warr, CG ;

Freeman, MR ;

Lessing, D ;

Kim, JH ;

Carlson, JR .

NEURON, 1999, 22 (02) :327-338

[9] Candidate taste receptors in Drosophila [J].

Clyne, PJ ;

Warr, CG ;

Carlson, JR .

SCIENCE, 2000, 287 (5459) :1830-1834

[10] Identification and characterization of human taste receptor genes belonging to the TAS2R family [J].

Conte, C ;

Ebeling, M ;

Marcuz, A ;

Nef, P ;

Andres-Barquin, PJ .

CYTOGENETIC AND GENOME RESEARCH, 2002, 98 (01) :45-53

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