Surface analyses and immune reactivities of major cell wall-associated proteins of group A streptococcus

被引：87

作者：

Cole, JN

Ramirez, RD

Currie, BJ

Cordwell, SJ

Djordjevic, SP

Walker, MJ ^{[1
]}

机构：

[1] Univ Wollongong, Sch Biol Sci, Wollongong, NSW 2522, Australia

[2] Charles Darwin Univ, Menzies Sch Hlth Res, Darwin, NT, Australia

[3] Macquarie Univ, Australian Proteome Anal Facil, Sydney, NSW 2109, Australia

[4] NSW Agr, Elizabeth Macarthur Agr Inst, Camden, NSW, Australia

来源：

INFECTION AND IMMUNITY | 2005年 / 73卷 / 05期

关键词：

D O I：

10.1128/IAI.73.5.3137-3146.2005

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A proteomic analysis was undertaken to identify cell wall-associated proteins of Streptococcus pyogenes. Seventy-four distinct cell wall-associated proteins were identified, 66 of which were novel. Thirty-three proteins were immunoreactive with pooled S. pyogenes-reactive human antisera. Biotinylation of the GAS cell surface identified 23 cell wall-associated proteins that are surface exposed.

引用

收藏

页码：3137 / 3146

页数：10

相关论文

共 41 条

[1] A ONE-STEP PROCEDURE FOR BIOTINYLATION AND CHEMICAL CROSS-LINKING OF LYMPHOCYTE SURFACE AND INTRACELLULAR MEMBRANE-ASSOCIATED MOLECULES [J].

ALTIN, JG ;

PAGLER, EB .

ANALYTICAL BIOCHEMISTRY, 1995, 224 (01) :382-389

[2] Invasive M1T1 group A Streptococcus undergoes a phase-shift in vivo to prevent proteolytic degradation of multiple virulence factors by SpeB [J].

Aziz, RK ;

Pabst, MJ ;

Jeng, A ;

Kansal, R ;

Low, DE ;

Nizet, V ;

Kotb, M .

MOLECULAR MICROBIOLOGY, 2004, 51 (01) :123-134

[3]

BURNETTE WN, 1981, ANAL BIOCHEM, V112, P195, DOI 10.1016/0003-2697(81)90281-5

[4] Identification of rgg-regulated exoproteins of Streptococcus pyogenes [J].

Chaussee, MS ;

Watson, RO ;

Smoot, JC ;

Musser, JM .

INFECTION AND IMMUNITY, 2001, 69 (02) :822-831

[5] Anchorless adhesins and invasins of Gram-positive bacteria: a new class of virulence factors [J].

Chhatwal, GS .

TRENDS IN MICROBIOLOGY, 2002, 10 (05) :205-208

[6] Characterisation of basic proteins from Spiroplasma melliferum using novel immobilised pH gradients [J].

Cordwell, SJ ;

Basseal, DJ ;

Bjellqvist, B ;

Shaw, DC ;

HumpherySmith, I .

ELECTROPHORESIS, 1997, 18 (08) :1393-1398

[7] BIOSYNTHESIS AND METABOLISM OF ARGININE IN BACTERIA [J].

CUNIN, R ;

GLANSDORFF, N ;

PIERARD, A ;

STALON, V .

MICROBIOLOGICAL REVIEWS, 1986, 50 (03) :314-352

[8] Pathogenesis of group A streptococcal infections [J].

Cunningham, MW .

CLINICAL MICROBIOLOGY REVIEWS, 2000, 13 (03) :470-+

[9]

Currie B J, 2000, Australas J Dermatol, V41, P139, DOI 10.1046/j.1440-0960.2000.00417.x

[10] Characterization of an isogenic mutant of Streptococcus pyogenes Manfredo lacking the ability to make streptococcal acid glycoprotein [J].

Degnan, BA ;

Fontaine, MC ;

Doebereiner, AH ;

Lee, JJ ;

Mastroeni, P ;

Dougan, G ;

Goodacre, JA ;

Kehoe, MA .

INFECTION AND IMMUNITY, 2000, 68 (05) :2441-2448

← 1 2 3 4 5 →