Investigation of secondary neutron dose for 18 MV dynamic MLC IMRT delivery

被引:72
作者
Howell, RM
Ferenci, MS
Hertel, NE
Fullerton, GD
机构
[1] Emory Univ, Sch Med, Dept Radiat Oncol, Atlanta, GA 30322 USA
[2] Georgia Inst Technol, Atlanta, GA 30332 USA
[3] Univ Texas, Hlth Sci Ctr, Dept Radiol Sci, San Antonio, TX 78229 USA
关键词
secondary neutrons; IMRT; Monte Carlo;
D O I
10.1118/1.1861162
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
Secondary neutron doses from the delivery of 18 MV conventional and intensity modulated radiation therapy (IMRT) treatment plans were compared. IMRT was delivered using dynamic multileaf collimation (MLC). Additional measurements were made with static MLC using a primary collimated field size of 10 x 10 cm(2) and MLC field sizes of 0 x 0, 5 x 5, and 10 x 10 cm(2). Neutron spectra were measured and effective doses calculated. The IMRT treatment resulted in a higher neutron fluence and higher dose equivalent. These increases were approximately the ratio of the monitor units. The static MLC measurements were compared to Monte Carlo calculations. The actual component dimensions and materials for the Varian Clinac 2100/2300C including the MLC were modeled with MCNPX to compute the neutron fluence due to neutron production in and around the treatment head. There is excellent agreement between the calculated and measured neutron fluence for the collimated field size of 10 x 10 cm(2) with the 0 x 0 cm(2) MLC field. Most of the neutrons at the detector location for this geometry are directly from the accelerator head with a small contribution from room scatter. Future studies are needed to investigate the effect of different beam energies used in IMRT incorporating the effects of scattered photon dose as well as secondary neutron dose. (c) 2005 American Association of Physicists in Medicine.
引用
收藏
页码:786 / 793
页数:8
相关论文
共 30 条
[1]  
*AAPM, 1987, 19 AAPM AM I PHYS
[2]  
*AM CANC SOC CANC, 2003, CA-CANCER J CLIN, V53, P5
[3]   Cross-section evaluations to 150 MeV for accelerator-driven systems and implementation in MCNPX [J].
Chadwick, MB ;
Young, PG ;
Chiba, S ;
Frankle, SC ;
Hale, GM ;
Hughes, HG ;
Koning, AJ ;
Little, RC ;
MacFarlane, RE ;
Prael, RE ;
Waters, LS .
NUCLEAR SCIENCE AND ENGINEERING, 1999, 131 (03) :293-328
[4]   A JPEG-like texture compression with adaptive quantization for 3D graphics application [J].
Chen, CH ;
Lee, CY .
VISUAL COMPUTER, 2002, 18 (01) :29-40
[5]  
CHU TC, 1999, P 1999 PART ACC C NY, P2531
[6]  
DIFILIPPO F, 2002, MED PHYS, V29, P1938
[7]   NEW METHODS FOR MEASURING NEUTRON-SPECTRA WITH ENERGY FROM 0.4EV TO 10 MEV BY TRACK AND ACTIVATION DETECTORS [J].
DOROSHENKO, JJ ;
KRAITOR, SN ;
KUZNETSOVA, TV ;
KUSHNEREVA, KK ;
LEONOV, ES .
NUCLEAR TECHNOLOGY, 1977, 33 (03) :296-304
[8]   Primary radiation therapy for localized prostate cancer [J].
Eng, TY ;
Thomas, CR ;
Herman, TS .
UROLOGIC ONCOLOGY, 2002, 7 (06) :239-257
[9]   Estimates of whole-body dose equivalent produced by beam intensity modulated conformal therapy [J].
Followill, D ;
Geis, P ;
Boyer, A .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1997, 38 (03) :667-672
[10]  
HENDRICKS JS, 2003, LAUR032202 LOS AL NA