Molecular Imaging of Hypoxia

被引：85

作者：

Chitneni, Satish K. ^{[2
]}

Palmer, Gregory M. ^{[1
]}

Zalutsky, Michael R. ^{[1
,2
]}

Dewhirst, Mark W. ^{[1
]}

机构：

[1] Duke Univ, Med Ctr, Dept Radiat Oncol, Durham, NC 27710 USA

[2] Duke Univ, Med Ctr, Dept Radiol, Durham, NC 27710 USA

来源：

JOURNAL OF NUCLEAR MEDICINE | 2011年 / 52卷 / 02期

关键词：

hypoxia; PET; optical imaging; nitroimidazole; POSITRON-EMISSION-TOMOGRAPHY; TUMOR HYPOXIA; NECK-CANCER; HEMOGLOBIN SATURATION; HEAD; PET; F-18-FLUOROMISONIDAZOLE; RADIOTHERAPY; MICROSCOPY;

D O I：

10.2967/jnumed.110.075663

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A wide variety of imaging approaches have been developed in the past few decades for monitoring tumor oxygenation and hypoxia in vivo. In particular, nuclear medicine has seen the development of several radiolabeled hypoxia markers and is the preferred method for imaging of tumor hypoxia. Hypoxia imaging is increasingly being used in the clinical setting and is progressing from a mere detection method to application in individualization of chemoradiotherapy.

引用

页码：165 / 168

页数：4

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