Eris: an automated estimator of protein stability

被引：325

作者：

Yin, Shuangye ^{[1
]}

Ding, Feng ^{[1
]}

Dokholyan, Nikolay V. ^{[1
]}

机构：

[1] Univ N Carolina, Sch Med, Dept Biochem & Biophys, Chapel Hill, NC 27599 USA

来源：

NATURE METHODS | 2007年 / 4卷 / 06期

关键词：

MUTATIONS;

D O I：

10.1038/nmeth0607-466

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

收藏

页码：466 / 467

页数：2

相关论文

共 6 条

[1] Large-scale prediction of protein geometry and stability changes for arbitrary single point mutations [J].

Bordner, AJ ;

Abagyan, RA .

PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2004, 57 (02) :400-413

[2] Emergence of protein fold families through rational design [J].

Ding, Feng ;

Dokholyan, Nikolay V. .

PLOS COMPUTATIONAL BIOLOGY, 2006, 2 (07) :725-733

[3] Predicting protein stability changes upon mutation using database-derived potentials: Solvent accessibility determines the importance of local versus non-local interactions along the sequence [J].

Gilis, D ;

Rooman, M .

JOURNAL OF MOLECULAR BIOLOGY, 1997, 272 (02) :276-290

[4] Predicting changes in the stability of proteins and protein complexes: A study of more than 1000 mutations [J].

Guerois, R ;

Nielsen, JE ;

Serrano, L .

JOURNAL OF MOLECULAR BIOLOGY, 2002, 320 (02) :369-387

[5] FREE-ENERGY CALCULATIONS - APPLICATIONS TO CHEMICAL AND BIOCHEMICAL PHENOMENA [J].

KOLLMAN, P .

CHEMICAL REVIEWS, 1993, 93 (07) :2395-2417

[6] Average assignment method for predicting the stability of protein mutants [J].

Saraboji, K ;

Gromiha, MM ;

Ponnuswamy, MN .

BIOPOLYMERS, 2006, 82 (01) :80-92