Diabetic ketoacidosis and hyperglycemic hyperosmolar nonketotic syndrome

被引:102
作者
Delaney, ME
Zisman, A
Kettyle, WM
机构
[1] Brigham & Womens Hosp, Div Endocrine Hypertens, Boston, MA 02115 USA
[2] Joslin Diabet Ctr, Sect Mol & Cellular Physiol, Boston, MA 02215 USA
[3] MIT, Dept Med, Cambridge, MA 02139 USA
关键词
D O I
10.1016/S0889-8529(05)70159-6
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Diabetic ketoacidosis (DKA) and hyperglycemic hyperosmolar nonketotic syndrome (HHNS) are life-threatening acute metabolic complications of diabetes mellitus. Although there are some important differences, the pathophysiology, the presenting clinical challenge, and the treatment of these metabolic derangements are similar. Each of these complications can be seen in type 1 or type 2 diabetes, although DKA is usually seen in patients with type 1 diabetes and HHNS in patients with type 2 disease. The clinical management of these syndromes involves careful evaluation and correction of the metabolic and volume status of the patient, identification and treatment of precipitating and comorbid conditions, a smooth transition to a long-term treatment regimen, and a plan to prevent recurrence.
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收藏
页码:683 / +
页数:24
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