Preparation and selective reactions of mixed bimetallic aromatic and heteroaromatic boron-magnesium reagents

被引:83
作者
Baron, O [1 ]
Knochel, P [1 ]
机构
[1] Univ Munich, Dept Chem & Biochem, D-81377 Munich, Germany
关键词
boronic esters; cross-coupling; heterocycles; magnesium; palladium;
D O I
10.1002/anie.200462928
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Chemical Equation Presented) It's all in the mix: The magnesiation of iodoaryl and iodoheteroaryl boronic esters with iPrMgCl·LiCl leads to mixed bimetallic compounds, which react with a variety of electrophiles to provide highly functionalized boronic esters (see scheme). Suzuki cross-coupling reactions of the resulting boronic esters afford various polyfunctional aromatic and heteroaromatic compounds. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.
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页码:3133 / 3135
页数:3
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