Preparation and selective reactions of mixed bimetallic aromatic and heteroaromatic boron-magnesium reagents

被引：83

作者：

Baron, O ^{[1
]}

Knochel, P ^{[1
]}

机构：

[1] Univ Munich, Dept Chem & Biochem, D-81377 Munich, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2005年 / 44卷 / 20期

关键词：

boronic esters; cross-coupling; heterocycles; magnesium; palladium;

D O I：

10.1002/anie.200462928

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Chemical Equation Presented) It's all in the mix: The magnesiation of iodoaryl and iodoheteroaryl boronic esters with iPrMgCl·LiCl leads to mixed bimetallic compounds, which react with a variety of electrophiles to provide highly functionalized boronic esters (see scheme). Suzuki cross-coupling reactions of the resulting boronic esters afford various polyfunctional aromatic and heteroaromatic compounds. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：3133 / 3135

页数：3

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