Hydroxyurea reacts with heme proteins to generate nitric oxide

被引：70

作者：

Pacelli, R

Taira, J

Cook, JA

Wink, DA

Krishna, MC

机构：

来源：

LANCET | 1996年 / 347卷 / 9005期

关键词：

D O I：

10.1016/S0140-6736(96)91378-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

收藏

页码：900 / 900

页数：1

相关论文

共 5 条

[1] ANTAGONISTIC ACTION OF IMIDAZOLINEOXYL N-OXIDES AGAINST ENDOTHELIUM-DERIVED RELAXING FACTOR .NO THROUGH A RADICAL REACTION [J].

AKAIKE, T ;

YOSHIDA, M ;

MIYAMOTO, Y ;

SATO, K ;

KOHNO, M ;

SASAMOTO, K ;

MIYAZAKI, K ;

UEDA, S ;

MAEDA, H .

BIOCHEMISTRY, 1993, 32 (03) :827-832

[2] EFFECT OF HYDROXYUREA ON THE FREQUENCY OF PAINFUL CRISES IN SICKLE-CELL-ANEMIA [J].

CHARACHE, S ;

TERRIN, ML ;

MOORE, RD ;

DOVER, GJ ;

BARTON, FB ;

ECKERT, SV ;

MCMAHON, RP ;

BONDS, DR ;

ORRINGER, E ;

JONES, S ;

STRAYHORN, D ;

ROSSE, W ;

PHILLIPS, G ;

PEACE, D ;

JOHNSONTELFAIR, A ;

MILNER, P ;

KUTLAR, A ;

TRACY, A ;

BALLAS, SK ;

ALLEN, GE ;

MOSHANG, J ;

SCOTT, B ;

STEINBERG, M ;

ANDERSON, A ;

SABAHI, V ;

PEGELOW, C ;

TEMPLE, D ;

CASE, E ;

HARRELL, R ;

CHILDERIE, S ;

EMBURY, S ;

SCHMIDT, B ;

DAVIES, D ;

KOSHY, M ;

TALISCHYZAHED, N ;

DORN, L ;

PENDARVIS, G ;

MCGEE, M ;

TELFER, M ;

DAVIS, A ;

CASTRO, O ;

FINKE, H ;

PERLIN, E ;

SITEMAN, J ;

GASCON, P ;

DIPAOLO, P ;

GARGIULO, S ;

ECKMAN, J ;

BAILEY, JH ;

PLATT, A .

NEW ENGLAND JOURNAL OF MEDICINE, 1995, 332 (20) :1317-1322

[3] HEMATOLOGIC RESPONSES OF PATIENTS WITH SICKLE-CELL DISEASE TO TREATMENT WITH HYDROXYUREA [J].

RODGERS, GP ;

DOVER, GJ ;

NOGUCHI, CT ;

SCHECHTER, AN ;

NIENHUIS, AW .

NEW ENGLAND JOURNAL OF MEDICINE, 1990, 322 (15) :1037-1045

[4] REACTIONS OF REDUCING XENOBIOTICS WITH OXYMYOGLOBIN - FORMATION OF METMYOGLOBIN, FERRYL MYOGLOBIN AND FREE-RADICALS - AN ELECTRON-SPIN-RESONANCE AND CHEMILUMINESCENCE STUDY [J].

STOLZE, K ;

NOHL, H .

BIOCHEMICAL PHARMACOLOGY, 1995, 49 (09) :1261-1267

[5]

YARBRO JW, 1992, SEMIN ONCOL, V19, P1