Pre-eclampsia - still a disease of theories?

被引：40

作者：

Higgins, JR ^{[1
]}

Brennecke, SP ^{[1
]}

机构：

[1] Royal Womens Hosp, Dept Perinatal Med, Melbourne, Vic 3053, Australia

来源：

CURRENT OPINION IN OBSTETRICS & GYNECOLOGY | 1998年 / 10卷 / 02期

关键词：

D O I：

10.1097/00001703-199804000-00009

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The pathophysiology of pre-eclampsia remains poorly understood. Moreover, there is no reliable predictive test and no effective prophylactic therapy for this disease. Advances have, however, recently been made in our understanding of the genetics of pre-eclampsia and in the processes which lead to abnormal trophoblastic invasion in pre-eclampsia. Prediction and prevention are intimately linked, and both problems will only be solved by further unravelling of the complex pathophysiology of pre-eclampsia. (C) 1998 Rapid Science ltd.

引用

页码：129 / 133

页数：5

共 43 条

[1] COLOCALIZATION OF VASCULAR ENDOTHELIAL GROWTH-FACTOR AND ITS FLT-1 RECEPTOR IN HUMAN PLACENTA [J].

AHMED, A ;

LI, XF ;

DUNK, C ;

WHITTLE, MJ ;

RUSHTON, DI ;

ROLLASON, T .

GROWTH FACTORS, 1995, 12 (03) :235-243

[2] ANGIOTENSINOGEN - A CANDIDATE GENE INVOLVED IN PREECLAMPSIA [J].

ARNGRIMSSON, R ;

PURANDARE, S ;

CONNOR, M ;

WALKER, JJ ;

BJORNSSON, S ;

SOUBRIER, F ;

KOTELEVTSEV, YV ;

GEIRSSON, RT ;

BJORNSSON, H .

NATURE GENETICS, 1993, 4 (02) :114-115

[3] Evidence for a familial pregnancy-induced hypertension locus in the eNOS-gene region [J].

Arngrimsson, R ;

Hayward, C ;

Nadaud, S ;

Baldursdottir, A ;

Walker, JJ ;

Liston, WA ;

Bjarnadottir, RI ;

Brock, DJH ;

Geirsson, RT ;

Connor, JM ;

Soubrier, F .

AMERICAN JOURNAL OF HUMAN GENETICS, 1997, 61 (02) :354-362

[4] ANALYSIS OF DIFFERENT INHERITANCE PATTERNS IN PREECLAMPSIA/ECLAMPSIA SYNDROME [J].

ARNGRIMSSON, R ;

BJORNSSON, H ;

GEIRSSON, RT .

HYPERTENSION IN PREGNANCY, 1995, 14 (01) :27-38

[5] Increased maternal plasma levels of soluble adhesion molecules (ICAM-1, VCAM-I, E-selectin) in preeclampsia [J].

Austgulen, R ;

Lien, E ;

Vince, G ;

Redman, CWG .

EUROPEAN JOURNAL OF OBSTETRICS GYNECOLOGY AND REPRODUCTIVE BIOLOGY, 1997, 71 (01) :53-58

[6] CALCIUM SUPPLEMENTATION TO PREVENT HYPERTENSIVE DISORDERS OF PREGNANCY [J].

BELIZAN, JM ;

VILLAR, J ;

GONZALEZ, L ;

CAMPODONICO, L ;

BERGEL, E .

NEW ENGLAND JOURNAL OF MEDICINE, 1991, 325 (20) :1399-1405

[7] Effect of calcium supplementation on pregnancy-induced hypertension and preeclampsia - A meta-analysis of randomized controlled trials [J].

Bucher, HC ;

Guyatt, GH ;

Cook, RJ ;

Hatala, R ;

Cook, DJ ;

Lang, JD ;

Hunt, D .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1996, 275 (14) :1113-1117

[8] CALCIUM SUPPLEMENTATION DURING PREGNANCY - A SYSTEMATIC REVIEW OF RANDOMIZED CONTROLLED TRIALS [J].

CARROLI, G ;

DULEY, L ;

BELIZAN, JM ;

VILLAR, J .

BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1994, 101 (09) :753-758

[9]

Chesley LC, 1978, Hypertensive disorders in pregnancy

[10] GENETIC-CONTROL OF SEVERE PRE-ECLAMPSIA [J].

COOPER, DW ;

LISTON, WA .

JOURNAL OF MEDICAL GENETICS, 1979, 16 (06) :409-416

← 1 2 3 4 5 →