FOXO transcription factors as regulators of immune homeostasis: Molecules to die for?

被引:139
作者
Birkenkamp, KU [1 ]
Coffer, PJ [1 ]
机构
[1] Univ Utrecht, Ctr Med, Dept Pulm Dis, NL-3584 CX Utrecht, Netherlands
关键词
FAMILY-MEMBER; PHOSPHOINOSITIDE; 3-KINASES; PHOSPHORYLATION SITES; CELL-SURVIVAL; FACTOR FKHR; LIFE-SPAN; FORKHEAD; PROTEIN; BINDING; DAF-16;
D O I
10.4049/jimmunol.171.4.1623
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
071005 [微生物学]; 100108 [医学免疫学];
摘要
引用
收藏
页码:1623 / 1629
页数:7
相关论文
共 42 条
[1]
Forkhead transcription factors contribute to execution of the mitotic programme in mammals [J].
Alvarez, B ;
Martinez, C ;
Burgering, BMT ;
Carrera, AC .
NATURE, 2001, 413 (6857) :744-747
[2]
Proapoptotic Bcl-2 relative bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity [J].
Bouillet, P ;
Metcalf, D ;
Huang, DCS ;
Tarlinton, DM ;
Kay, TWH ;
Köntgen, F ;
Adams, JM ;
Strasser, A .
SCIENCE, 1999, 286 (5445) :1735-1738
[3]
Inhibition of nuclear import by protein kinase B (Akt) regulates the subcellular distribution and activity of the forkhead transcription factor AFX [J].
Brownawell, AM ;
Kops, GJPL ;
Macara, IG ;
Burgering, BMT .
MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (10) :3534-3546
[4]
14-3-3 transits to the nucleus and participates in dynamic nucleocytoplasmic transport [J].
Brunet, A ;
Kanai, F ;
Stehn, J ;
Xu, J ;
Sarbassova, D ;
Frangioni, JV ;
Dalal, SN ;
DeCaprio, JA ;
Greenberg, ME ;
Yaffe, MB .
JOURNAL OF CELL BIOLOGY, 2002, 156 (05) :817-828
[5]
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a) [J].
Brunet, A ;
Park, J ;
Tran, H ;
Hu, LS ;
Hemmings, BA ;
Greenberg, ME .
MOLECULAR AND CELLULAR BIOLOGY, 2001, 21 (03) :952-965
[6]
Akt promotes cell survival by phosphorylating and inhibiting a forkhead transcription factor [J].
Brunet, A ;
Bonni, A ;
Zigmond, MJ ;
Lin, MZ ;
Juo, P ;
Hu, LS ;
Anderson, MJ ;
Arden, KC ;
Blenis, J ;
Greenberg, ME .
CELL, 1999, 96 (06) :857-868
[7]
OXIDATIVE STRESS AS A MEDIATOR OF APOPTOSIS [J].
BUTTKE, TM ;
SANDSTROM, PA .
IMMUNOLOGY TODAY, 1994, 15 (01) :7-10
[8]
Phosphatidylinositol 3-kinase signaling inhibits DAF-16 DNA binding and function via 14-3-3-dependent and 14-3-3-independent pathways [J].
Cahill, CM ;
Tzivion, G ;
Nasrin, N ;
Ogg, S ;
Dore, J ;
Ruvkun, G ;
Alexander-Bridges, M .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (16) :13402-13410
[9]
Cyclic AMP-induced forkhead transcription factor, FKHR, cooperates with CCAAT/enhancer-binding protein β in differentiating human endometrial stromal cells [J].
Christian, M ;
Zhang, XH ;
Schneider-Merck, T ;
Unterman, TG ;
Gellersen, B ;
White, JO ;
Brosens, JJ .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2002, 277 (23) :20825-20832
[10]
Coffer PJ, 1998, BIOCHEM J, V335, P1