Hexagonally packed DNA within bacteriophage T7 stabilized by curvature stress

被引：92

作者：

Odijk, T ^{[1
]}

机构：

[1] Delft Univ Technol, Fac Chem Engn & Mat Sci, NL-2600 GA Delft, Netherlands

来源：

BIOPHYSICAL JOURNAL | 1998年 / 75卷 / 03期

关键词：

D O I：

10.1016/S0006-3495(98)74041-X

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

A continuum computation is proposed for the bending stress stabilizing DNA that is hexagonally packed within bacteriophage T7. Because the inner radius of the DNA spool is rather small, the stress of the curved DNA genome is strong enough to balance its electrostatic self-repulsion so as to form a stable hexagonal phase. The theory is in accord with the microscopically determined structure of bacteriophage T7 filled with DNA within the experimental margin of error.

引用

页码：1223 / 1227

页数：5

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