Polymer-supported Lewis bases for the Baylis-Hillman reaction

被引：54

作者：

Huang, JW ^{[1
]}

Shi, M ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organomet Chem, Shanghai 200032, Peoples R China

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2003年 / 345卷 / 08期

关键词：

acrylic esters; arenecarbaldehydes; Baylis-Hillman reaction; Lewis bases; methyl vinyl ketone (MVK); PEG(4600)-(PPh2)(2); polyDMAP; N-tosylimines (ArCH=NTs);

D O I：

10.1002/adsc.200303072

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

The use of polymer-supported Lewis bases such as PEG(4600)-(PPh2)(2) and poly(DMAP) in the Baylis-Hillman reactions of N-tosylimines (ArCH=NTs) 1 or the corresponding arenecarbaldehydes with alpha,beta-unsaturated ketones has been investigated. The corresponding Baylis-Hillman adducts are obtained in good yields. The polymer-supported Lewis bases can be easily recovered by filtration and the Lewis base PEG4600-(PPh2)(2) can be reproduced by reduction with LiAlH4 and CeCl3.

引用

页码：953 / 958

页数：6

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