Forward and reverse hippocampal place-cell sequences during ripples

被引：714

作者：

Diba, Kamran ^{[1
]}

Buzsaki, Gyoergy ^{[1
]}

机构：

[1] Rutgers State Univ, Ctr Mol & Behav Neurobiol, Newark, NJ 07102 USA

来源：

NATURE NEUROSCIENCE | 2007年 / 10卷 / 10期

关键词：

D O I：

10.1038/nn1961

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We report that temporal spike sequences from hippocampal place neurons of rats on an elevated track recurred in reverse order at the end of a run, but in forward order in anticipation of the run, coinciding with sharp waves. Vector distances between the place fields were reflected in the temporal structure of these sequences. This bidirectional re-enactment of temporal sequences may contribute to the establishment of higher-order associations in episodic memory.

引用

页码：1241 / 1242

页数：2

共 16 条

[1] 2-STAGE MODEL OF MEMORY TRACE FORMATION - A ROLE FOR NOISY BRAIN STATES [J].

BUZSAKI, G .

NEUROSCIENCE, 1989, 31 (03) :551-570

[2] Sleep Enforces the Temporal Order in Memory [J].

Drosopoulos, Spyridon ;

Windau, Eike ;

Wagner, Ullrich ;

Born, Jan .

PLOS ONE, 2007, 2 (04)

[3] The hippocampus, memory, and place cells: Is it spatial memory or a memory space? [J].

Eichenbaum, H ;

Dudchenko, P ;

Wood, E ;

Shapiro, M ;

Tanila, H .

NEURON, 1999, 23 (02) :209-226

[4] Prospective and retrospective memory coding in the hippocampus [J].

Ferbinteanu, J ;

Shapiro, ML .

NEURON, 2003, 40 (06) :1227-1239

[5] Reverse replay of behavioural sequences in hippocampal place cells during the awake state [J].

Foster, DJ ;

Wilson, MA .

NATURE, 2006, 440 (7084) :680-683

[6] The temporal context model in spatial navigation and relational learning: Toward a common explanation of medial temporal lobe function across domains [J].

Howard, MW ;

Fotedar, MS ;

Datey, AV ;

Hasselmo, ME .

PSYCHOLOGICAL REVIEW, 2005, 112 (01) :75-116

[7] Position reconstruction from an ensemble of hippocampal place cells: Contribution of theta phase coding [J].

Jensen, O ;

Lisman, JE .

JOURNAL OF NEUROPHYSIOLOGY, 2000, 83 (05) :2602-2609

[8] Associative retrieval processes in free recall [J].

Kahana, MJ .

MEMORY & COGNITION, 1996, 24 (01) :103-109

[9] Memory of sequential experience in the hippocampus during slow wave sleep [J].

Lee, AK ;

Wilson, MA .

NEURON, 2002, 36 (06) :1183-1194

[10] Experience-dependent, asymmetric expansion of hippocampal place fields [J].

Mehta, MR ;

Barnes, CA ;

McNaughton, BL .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (16) :8918-8921

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