Biobanking for Europe

被引:151
作者
Yuille, Martin [12 ]
van Ommen, Gert-Jan [1 ]
Brechot, Christian [2 ]
Cambon-Thomsen, Anne [3 ]
Dagher, Georges [4 ]
Landegren, Ulf [5 ]
Litton, Jan-Eric [6 ]
Pasterk, Markus [7 ]
Peltonen, Leena [8 ]
Taussig, Mike [9 ]
Wichmann, H-Erich [10 ]
Zatloukal, Kurt [11 ]
机构
[1] CMSB Dept Human Genet, LUMC, Netherlands
[2] Inst Natl Sante & Rech Med, Paris, France
[3] Univ Toulouse 3, UMR Inserm, U 558, F-31062 Toulouse, France
[4] INSERM Tolbiac, Paris, France
[5] Uppsala Univ, Dept Genet & Pathol, SE-75185 Uppsala, Sweden
[6] Karolinska Inst, Dept Med Epidemiol & Biostat, Stockholm, Sweden
[7] Int Agcy Res Canc, F-69372 Lyon, France
[8] Biomed Helsinki, Natl Publ Hlth Inst, Helsinki, Finland
[9] Babraham Inst, Cambridge CB22 3AT, England
[10] GSF Munich, Inst Epidemiol, Munich, Germany
[11] Med Univ Graz, Inst Pathol, Graz, Austria
[12] Univ Manchester, Sch Translat Med, CIGMR, UK DNA Banking Network, Manchester M13 9PT, Lancs, England
基金
英国医学研究理事会;
关键词
epidemiology; pathology; genetics; biobanks; databases; ethics; funding;
D O I
10.1093/bib/bbm050
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Biobanks are well-organized resources comprising biological samples and associated information that are accessible to scientific investigation. Across Europe, millions of samples with related data are held in different types of collections. While individual collections can be well organized and accessible, the resources are subject to fragmentation, insecurity of funding and incompleteness. To address these issues, a Biobanking and BioMolecular Resources Infrastructure (BBMRI) is to be developed across Europe, thereby implementing a European roadmap for research infrastructures that was developed by a forum of EU member states and that has been received by the European Commission. In this review, we describe the work involved in preparing for the construction of BBMRI in a European and global context.
引用
收藏
页码:14 / 24
页数:11
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