Preterm birth, vascular function, and risk factors for atherosclerosis

被引：100

作者：

Singhal, A

Kattenhorn, M

Cole, TJ

Deanfield, J

Lucas, A

机构：

[1] Inst Child Hlth, MRC, Childrens Nutr Res Ctr, London WC1N 1EH, England

[2] Inst Child Hlth, Dept Vasc Physiol, London WC1N 1EH, England

[3] Inst Child Hlth, Dept Paediat Epidemiol & Biostat, London WC1N 1EH, England

来源：

LANCET | 2001年 / 358卷 / 9288期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/S0140-6736(01)06276-6

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Low birthweight may predispose to the development of atherosclerosis later In life. We have tested the hypothesis that low birthweight as a result of preterm birth Is associated with reduced flow-mediated endothelial-dependent vasodilation (FMD), which Is an early stage In the development of atherosclerosis. Mean FMD In adolescents born preterm who had a low birthweight did not differ from that for controls born at term (0.225 mm vs 0.220 mm, SD 0.1 for both means, p = 0.78). Our findings indicate that low birthweight attributable to prematurity does not Increase the risk of vascular disease later in life.

引用

页码：1159 / 1160

页数：2

共 5 条

[1] Adult cardiovascular risk factors in premature babies [J].