Unraveling the pathway of lipoic acid biosynthesis

被引:43
作者
Booker, SJ [1 ]
机构
[1] Penn State Univ, Dept Biochem & Mol Biol, University Pk, PA 16802 USA
来源
CHEMISTRY & BIOLOGY | 2004年 / 11卷 / 01期
关键词
D O I
10.1016/j.chembiol.2004.01.002
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Lipoic acid is almost universally required for aerobic metabolism. However, the mechanism for its synthesis and incorporation into proteins has remained elusive. A groundbreaking study published in the December issue of Chemistry & Biology [20] uncovers critical features of the lipoic acid biosynthetic pathway.
引用
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页码:10 / 12
页数:3
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