Sub-micrometer particulate air pollution and cardiovascular mortality in Beijing, China

被引:107
作者
Breitner, Susanne [1 ,2 ]
Liu, Liqun [1 ,2 ,3 ]
Cyrys, Josef [1 ,4 ]
Brueske, Irene [5 ]
Franck, Ulrich [6 ]
Schlink, Uwe [6 ]
Leitte, Arne Marian [6 ]
Herbarth, Olf [6 ,7 ]
Wiedensohler, Alfred [8 ]
Wehner, Birgit [8 ]
Hu, Min [9 ]
Pan, Xiao-Chuan [3 ]
Wichmann, H-Erich [2 ,5 ]
Peters, Annette [1 ,10 ]
机构
[1] Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Epidemiol 2, D-85764 Neuherberg, Germany
[2] Univ Munich, IBE Chair Epidemiol, Munich, Germany
[3] Peking Univ, Hlth Sci Ctr, Sch Publ Hlth, Beijing 100871, Peoples R China
[4] Univ Augsburg, Ctr Environm Sci, Augsburg, Germany
[5] Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Inst Epidemiol 1, D-85764 Neuherberg, Germany
[6] UFZ Helmholtz Ctr Environm Res, Core Facil Studies, Leipzig, Germany
[7] Univ Leipzig, Leipzig, Germany
[8] Leibniz Inst Tropospher Res IfT, Leipzig, Germany
[9] Peking Univ, Coll Environm Sci & Engn, State Key Joint Lab Environm Simulat & Pollut Con, Beijing 100871, Peoples R China
[10] Helmholtz Zentrum Munchen, German Res Ctr Environm Hlth, Focus Network Nanoparticles & Hlth NanoHlth, D-85764 Neuherberg, Germany
关键词
Beijing; Cardiovascular mortality; Particle number; Particle surface area; Particle mass; Air mass history; PARTICLE NUMBER CONCENTRATION; TIME-SERIES; ULTRAFINE PARTICLES; SIZE; AEROSOL; MATTER; MASS; FINE;
D O I
10.1016/j.scitotenv.2011.08.023
中图分类号
X [环境科学、安全科学];
学科分类号
083001 [环境科学];
摘要
Background: While the link between particulate matter and cardiovascular mortality is well established, it is not fully investigated and understood which properties of the aerosol might be responsible for the health effects, especially in polluted mega-city areas. Objectives: Our goal was to explore the association between daily cardiovascular mortality and different particle metrics in the sub-micrometer range in Beijing, China. Methods: We obtained daily counts of cause-specific cardiovascular deaths in the Beijing urban area for the period March 2004 to August 2005. Concurrently, continuous measurements of particle number size distributions were performed. Particle number concentrations (NC) between 0.003 mu m and 0.8 mu m were converted to particle mass and surface area concentrations assuming spherical particles. Semi-parametric Poisson regression models adjusting for trend, seasonality, day of the week, and meteorology were used to estimate immediate, delayed and cumulative particle effects. Additionally, effect modification by air mass origin was investigated. Results: We observed associations between daily cardiovascular mortality and particle NC for a 2-days delay. Moreover, nearly all particle metrics showed 2-days delayed associations with ischemic heart disease mortality. The strongest association was found for particle NC in the size range 0.03-0.1 mu m (7.1% increase in daily mortality with a 95%-confidence interval of 2.9%-11.5%, per an increase of 6250 particles/cm(3)). Results for surface and mass concentrations with a lag of two days indicated effect modification by air mass origin, whereas effects of particle NC were not modified. Conclusions: Results show an elevated risk of cardiovascular mortality in Beijing from short-term exposure to particulate air pollution in the sub-micrometer range. Results also indicate that locally produced smaller particles and regionally transported particles may exhibit different effects in Beijing. (C) 2011 Elsevier B.V. All rights reserved.
引用
收藏
页码:5196 / 5204
页数:9
相关论文
共 38 条
[1]
Aerosol particle number concentration measurements in five European cities using TSI-3022 condensation particle counter over a three-year period during health effects pollution on susceptible subpopulations [J].
Aalto, P ;
Hämeri, K ;
Paatero, P ;
Kulmala, M ;
Bellander, T ;
Berglind, N ;
Bouso, L ;
Castano-Vinyals, G ;
Sunyer, J ;
Cattani, G ;
Marconi, A ;
Cyrys, J ;
von Klot, S ;
Peters, A ;
Zetzsche, K ;
Lanki, T ;
Pekkanen, J ;
Nyberg, F ;
Sjövall, B ;
Forastiere, F .
JOURNAL OF THE AIR & WASTE MANAGEMENT ASSOCIATION, 2005, 55 (08) :1064-1076
[2]
[Anonymous], HLTH EFF I
[3]
[Anonymous], ASS SIZE RESOLVED NU
[4]
[Anonymous], GEOPHYS RES LETT
[5]
[Anonymous], DAILY MORTALITY FI 1
[6]
Urban Ambient Particle Metrics and Health A Time-series Analysis [J].
Atkinson, Richard W. ;
Fuller, Gary W. ;
Anderson, H. Ross ;
Harrison, Roy M. ;
Armstrong, Ben .
EPIDEMIOLOGY, 2010, 21 (04) :501-511
[7]
Beijing Municipal Bureau of Statistics, 2006, BEIJ STAT YB 2006
[8]
Design of a DMA-based size spectrometer for a large particle size range and stable operation [J].
Birmili, W ;
Stratmann, F ;
Wiedensohler, A .
JOURNAL OF AEROSOL SCIENCE, 1999, 30 (04) :549-553
[9]
Cardiovascular effects of air pollution [J].
Brook, Robert D. .
CLINICAL SCIENCE, 2008, 115 (5-6) :175-187
[10]
Particulate Matter Air Pollution and Cardiovascular Disease An Update to the Scientific Statement From the American Heart Association [J].
Brook, Robert D. ;
Rajagopalan, Sanjay ;
Pope, C. Arden, III ;
Brook, Jeffrey R. ;
Bhatnagar, Aruni ;
Diez-Roux, Ana V. ;
Holguin, Fernando ;
Hong, Yuling ;
Luepker, Russell V. ;
Mittleman, Murray A. ;
Peters, Annette ;
Siscovick, David ;
Smith, Sidney C., Jr. ;
Whitsel, Laurie ;
Kaufman, Joel D. .
CIRCULATION, 2010, 121 (21) :2331-2378