Distribution, determinants and reference values of left ventricular parameters in the general population -: Results of the MONICA/KORA echocardiography studies

被引:15
作者
Kuch, B
Schunkert, H
Muscholl, M
Döring, A
von Scheidt, W
Hense, HW
机构
[1] Klinikum Augsburg, Med Klin 1, D-86156 Augsburg, Germany
[2] Univ Klinikum Schleswig Holstein, Med Klin 2, Lubeck, Germany
[3] Klinikum Univ Regensburg, Klin & Poliklin Innere Med 2, Regensburg, Germany
[4] GSF, Forschungszentrum Umwelt & Gesundheit, Inst Epidemiol, Neuherberg, Germany
[5] Univ Munster, Inst Epidemiol & Sozialmed, D-4400 Munster, Germany
关键词
echocardiography; left ventricular hypertrophy; gender differences; obesity; hypertension;
D O I
10.1055/s-2005-858245
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
For successful fighting against the burden of cardiovascular disease in the community a comprehensive knowledge about the prevalence and the impact of underlying risk factors is important. The present paper summarises some studies undertaken on more than 2000 persons from the MONICA/KORA-studies (parts of S1 and S3) where left ventricular mass (LVM) and other left ventricular parameters were determined by echocardiography. We especially investigated the associations of LVM with blood pressure and obesity. A special focus was on sex-specific factors in the determination of LVM and the influence of different indices of body size when normalising LVM. It could be shown that hypertension and obesity are major determinants of IV hypertrophy. Especially women with both hypertension and obesity on showed a high prevalence of concentric hypertrophy, significantly more than men. We also showed that the prevalence of IV hypertrophy in a representative sample of the general population (25 to 74 years) is 17.5% for men, and 18.5% for women. This underscores the need for primary and secondary prevention regarding the development of LV hypertrophy. Finally, our data in a selected group of normal subjects (reference sample) may be used for the development of reference values for left ventricular parameters in the general German population.
引用
收藏
页码:S68 / S73
页数:6
相关论文
共 36 条
[1]   WHICH DEFINITION FOR ECHOCARDIOGRAPHIC LEFT-VENTRICULAR HYPERTROPHY [J].
ABERGEL, E ;
TASE, M ;
BOHLENDER, J ;
MENARD, J ;
CHATELLIER, G .
AMERICAN JOURNAL OF CARDIOLOGY, 1995, 75 (07) :498-502
[2]  
ARANOW W, 1991, AM J CARDIOL, V67, P295
[3]   GENDER DIFFERENCES IN OLDER PATIENTS WITH PRESSURE-OVERLOAD HYPERTROPHY OF THE LEFT-VENTRICLE [J].
AURIGEMMA, GP ;
GAASCH, WH .
CARDIOLOGY, 1995, 86 (04) :310-317
[4]   Relations of left ventricular mass to fat-free and adipose body mass - The strong heart study [J].
Bella, JN ;
Devereux, RB ;
Roman, MJ ;
O'Grady, MJ ;
Welty, TK ;
Lee, ET ;
Fabsitz, RR ;
Howard, BV .
CIRCULATION, 1998, 98 (23) :2538-2544
[5]  
CABRAL AM, 1984, J HYPERTENS, V2, P85
[6]   VALUE OF ECHOCARDIOGRAPHIC MEASUREMENT OF LEFT-VENTRICULAR MASS IN PREDICTING CARDIOVASCULAR MORBID EVENTS IN HYPERTENSIVE MEN [J].
CASALE, PN ;
DEVEREUX, RB ;
MILNER, M ;
ZULLO, G ;
HARSHFIELD, GA ;
PICKERING, TG ;
LARAGH, JH .
ANNALS OF INTERNAL MEDICINE, 1986, 105 (02) :173-178
[7]   LEFT-VENTRICULAR HYPERTROPHY IS ASSOCIATED WITH WORSE SURVIVAL INDEPENDENT OF VENTRICULAR-FUNCTION AND NUMBER OF CORONARY-ARTERIES SEVERELY NARROWED [J].
COOPER, RS ;
SIMMONS, BE ;
CASTANER, A ;
SANTHANAM, V ;
GHALI, J ;
MAR, M .
AMERICAN JOURNAL OF CARDIOLOGY, 1990, 65 (07) :441-445
[8]   INDEXING LEFT-VENTRICULAR MASS TO ACCOUNT FOR DIFFERENCES IN BODY-SIZE IN CHILDREN AND ADOLESCENTS WITHOUT CARDIOVASCULAR-DISEASE [J].
DANIELS, SR ;
KIMBALL, TR ;
MORRISON, JA ;
KHOURY, P ;
MEYER, RA .
AMERICAN JOURNAL OF CARDIOLOGY, 1995, 76 (10) :699-701
[9]   LEFT-VENTRICULAR MASS AND BODY SIZE IN NORMOTENSIVE CHILDREN AND ADULTS - ASSESSMENT OF ALLOMETRIC RELATIONS AND IMPACT OF OVERWEIGHT [J].
DESIMONE, G ;
DANIELS, SR ;
DEVEREUX, RB ;
MEYER, RA ;
ROMAN, MJ ;
DEDIVITIIS, O ;
ALDERMAN, MH .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1992, 20 (05) :1251-1260
[10]   Relations of left ventricular mass to demographic and hemodynamic variables in American Indians - The Strong Heart Study [J].
Devereux, RB ;
Roman, MJ ;
deSimone, G ;
OGrady, MJ ;
Paranicas, M ;
Yeh, JL ;
Fabsitz, RR ;
Howard, BV .
CIRCULATION, 1997, 96 (05) :1416-1423