Cross-presentation: A general mechanism for CTL immunity and tolerance

被引：206

作者：

Carbone, FR

Kurts, C

Bennett, SRM

Miller, JFAP

Heath, WR

机构：

[1] Alfred Hosp, Monash Med Sch, Dept Pathol & Immunol, Prahran, Vic 3181, Australia

[2] Royal Melbourne Hosp, Walter & Eliza Hall Inst Med Res, PO Royal Melbourne Hosp, Parkville, Vic 3050, Australia

来源：

IMMUNOLOGY TODAY | 1998年 / 19卷 / 08期

关键词：

D O I：

10.1016/S0167-5699(98)01301-2

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

MHC class I-restricted presentation is usually associated with the processing of endogenous antigens. However, this restriction element can present antigens that do not originate within the presenting cells. Here, Francis Carbone and colleagues describe how such cross-presentation is critical for cytotoxic T-cell surveillance of peripheral antigens, both self and foreign, located outside the secondary lymphoid compartment.

引用

收藏

页码：368 / 373

页数：6

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