A menage a trois in two configurations

被引：17

作者：

Sadler, JE ^{[1
]}

机构：

[1] Washington Univ, Dept Med, Howard Hughes Med Inst, St Louis, MO 63110 USA

[2] Washington Univ, Dept Biochem & Mol Biophys, St Louis, MO 63110 USA

来源：

SCIENCE | 2003年 / 301卷 / 5630期

关键词：

D O I：

10.1126/science.1087734

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

[No abstract available]

引用

页码：177 / 179

页数：3

共 16 条

[1]

BODE W, 1992, PROTEIN SCI, V1, P426

[2] Modulation of α-thrombin function by distinct interactions with platelet glycoprotein Ib-α [J].

Celikel, R ;

McClintock, RA ;

Roberts, JR ;

Mendolicchio, GL ;

Ware, J ;

Varughese, KI ;

Ruggeri, ZM .

SCIENCE, 2003, 301 (5630) :218-221

[3] Thrombin signalling and protease-activated receptors [J].

Coughlin, SR .

NATURE, 2000, 407 (6801) :258-264

[4] Binding of thrombin to glycoprotein Ib accelerates the hydrolysis of Par-1 on intact platelets [J].

De Candia, E ;

Hall, SW ;

Rutella, S ;

Landolfi, R ;

Andrews, RK ;

De Cristofaro, R .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (07) :4692-4698

[5] The Asp272-Glu282 region of platelet glycoprotein Ibα interacts with the heparin-binding site of α-thrombin and protects the enzyme from the heparin-catalyzed inhibition by antithrombin III [J].

De Cristofaro, R ;

De Candia, E ;

Rutella, S ;

Weitz, JI .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (06) :3887-3895

[6] Structural and functional mapping of the thrombin domain involved in the binding to the platelet glycoprotein Ib [J].

De Cristofaro, R ;

De Candia, E ;

Landolfi, R ;

Rutella, S ;

Hall, SW .

BIOCHEMISTRY, 2001, 40 (44) :13268-13273

[7] Crystal structure of the GpIbα-thrombin complex essential for platelet aggregation [J].

Dumas, JJ ;

Kumar, R ;

Seehra, J ;

Somers, WS ;

Mosyak, L .

SCIENCE, 2003, 301 (5630) :222-226

[8] Structures of glycoprotein Ibα and its complex with von Willebrand factor A1 domain [J].

Huizinga, EG ;

Tsuji, S ;

Romijn, RAP ;

Schiphorst, ME ;

de Groot, PG ;

Sixma, JJ ;

Gros, P .

SCIENCE, 2002, 297 (5584) :1176-1179

[9]

JANDROTPERRUS M, 1991, THROMB HAEMOSTASIS, V66, P300

[10] Platelet glycoprotein Ibα binds to thrombin anion-binding exosite II inducing allosteric changes in the activity of thrombin [J].

Li, CQ ;

Vindigni, A ;

Sadler, JE ;

Wardell, MR .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2001, 276 (09) :6161-6168

← 1 2 →