Pathways for Cytokine Secretion

被引：175

作者：

Stanley, Amanda C. ^{[1
]}

Lacy, Paige ^{[2
]}

机构：

[1] Univ Queensland, Inst Mol Biosci, St Lucia, Qld, Australia

[2] Univ Alberta, Dept Med, Pulm Res Grp, Edmonton, AB, Canada

来源：

PHYSIOLOGY | 2010年 / 25卷 / 04期

基金：

加拿大健康研究院; 英国医学研究理事会;

关键词：

NECROSIS-FACTOR-ALPHA; MONONUCLEAR-CELL-CULTURES; TRANS-GOLGI NETWORK; HUMAN EOSINOPHILS; TNF-ALPHA; REGULATED SECRETION; PIECEMEAL DEGRANULATION; MEMBRANE-PROTEIN; MAST-CELLS; ACTIVATED MACROPHAGES;

D O I：

10.1152/physiol.00017.2010

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Cytokine secretion is a widely studied process, although little is known regarding the specific mechanisms that regulate cytokine release. Recent findings have shed light on some of the precise molecular pathways that regulate the packaging of newly synthesized cytokines from immune cells. These findings begin to elucidate pathways and mechanisms that underpin cytokine release in all cells. In this article, we review the highlights of some of these novel discoveries.

引用

页码：218 / 229

页数：12

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