New synthetic route for dextran graft copolymers containing thermo-responsive polymers

被引：20

作者：

Huh, KM ^{[1
]}

Kumashiro, Y ^{[1
]}

Ooya, T ^{[1
]}

Yui, N ^{[1
]}

机构：

[1] Japan Adv Inst Sci & Technol, Sch Mat Sci, Tatsunokuchi, Ishikawa 9231292, Japan

来源：

POLYMER JOURNAL | 2001年 / 33卷 / 01期

关键词：

dextran; graft copolymer; poly(N-isopropylacrylamide-co-N; N-dimethylacrylamide); thermo-responsive graft; enzymatic degradation;

D O I：

10.1295/polymj.33.108

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

A new synthetic route to introduce thermo-responsive grafts onto dextrans was developed so that changing synthetic conditions can easily control the structures of graft copolymers such as graft length and number. The resulting method involves the synthesis of semitelechelic poly(NIPAAM-co-DMAAm)s with a hydrazide end-group, and coupling reaction with p-nitrophenyl chloroformate-activated dextran. Dextran graft copolymers exhibited an anomalous enzymatic degradation with temperature change.

引用

页码：108 / 111

页数：4

共 12 条

[1] Enzymatic degradation of cross-linked dextrans [J].

Franssen, O ;

van Ooijen, RD ;

de Boer, D ;

Maes, RAA ;

Hennink, WE .

MACROMOLECULES, 1999, 32 (09) :2896-2902

[2] SYNTHESIS AND CHARACTERIZATION OF POLY(OXYETHYLENE) MODIFIED DEXTRANS [J].

HOSTE, K ;

BRUNEEL, D ;

DEMARRE, A ;

DESCHRIJVER, F ;

SCHACHT, E .

MACROMOLECULAR RAPID COMMUNICATIONS, 1994, 15 (09) :697-704

[3]

Huh KM, 2000, MACROMOL CHEM PHYSIC, V201, P613, DOI 10.1002/(SICI)1521-3935(20000301)201:5<613::AID-MACP613>3.0.CO

[4]

2-I

[5]

Kurisawa M, 1998, MACROMOL CHEM PHYSIC, V199, P2613, DOI 10.1002/(SICI)1521-3935(19981101)199:11<2613::AID-MACP2613>3.0.CO

[6]

2-W

[7]

Kurisawa M, 1998, MACROMOL CHEM PHYSIC, V199, P705, DOI 10.1002/(SICI)1521-3935(19980401)199:4<705::AID-MACP705>3.0.CO

[8]

2-9

[9]

Kurisawa M, 1998, MACROMOL CHEM PHYSIC, V199, P1547, DOI 10.1002/(SICI)1521-3935(19980801)199:8<1547::AID-MACP1547>3.0.CO

[10]

2-E

← 1 2 →