Season of birth in females with anorexia nervosa in northeast Scotland

Objective: To determine whether patients with anorexia nervosa exhibit an abnormal pattern in their season of birth. Method: Case records of female patients presenting to secondary services in Northeast Scotland from 1965 to 1997 who received a clinical diagnosis of anorexia nervosa were examined. The months of birth of the 446 anorexic patients with a confirmed diagnosis were compared with 5,766 female control subjects born locally in 1951, 1961, 1971, and 1981. Results: Patients with anorexia nervosa had an excess of births in the first 6 months of the year (p = .013). The greatest excess was from March to June. Discussion: This provides further evidence that birth dates of anorexics peak in the late spring and early summer. There are parallels with the epidemiology of schizophrenia. The evidence suggests that a seasonally fluctuating factor, most plausibly an intrauterine effect of common infectious agents during the winter months, is of etiological significance. (C) 2001 by John Wiley & Sons, Inc.