In vitro postantibiotic effects of rifapentine, isoniazid, and moxifloxacin against Mycobacterium tuberculosis

被引：27

作者：

Chan, CY ^{[1
]}

Au-Yeang, C

Yew, WW

Leung, CC

Cheng, AFB

机构：

[1] Chinese Univ Hong Kong, Prince Wales Hosp, Fac Med, Dept Microbiol, Shatin, Hong Kong, Peoples R China

[2] Grantham Hosp, TB & Chest Unit, Aberdeen, Hong Kong, Peoples R China

[3] Dept Hlth, TB & Chest Serv, Hong Kong, Hong Kong, Peoples R China

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2004年 / 48卷 / 01期

关键词：

D O I：

10.1128/AAC.48.1.340-343.2004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Postantibiotic effects (PAEs) of rifapentine, isoniazid, and moxifloxacin against Mycobacterium tuberculosis ATCC 27294 were studied using a radiometric culture system. Rifapentine at 20 mg/liter gave the longest PAE (104 h) among the drugs used alone. The combinations of rifapentine plus isoniazid, rifapentine plus moxifloxacin, and isoniazid plus moxifloxacin gave PAEs of 136.5, 59.0, and 8.3 h, respectively.

引用

页码：340 / 343

页数：4

共 24 条

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