Wnt Signaling Related to Subchondral Bone Density and Cartilage Degradation in Osteoarthritis

被引：14

作者：

Burr, David B. ^{[1
,2
]}

Utreja, Achint ^{[3
]}

机构：

[1] Indiana Univ Sch Med, Indianapolis, IN 46202 USA

[2] Indiana Univ Purdue Univ, Indianapolis, IN 46202 USA

[3] Indiana Univ, Sch Dent, Indianapolis, IN USA

来源：

ARTHRITIS & RHEUMATOLOGY | 2018年 / 70卷 / 02期

关键词：

TRABECULAR BONE; ARTICULAR-CARTILAGE; CYNOMOLGUS MACAQUES; SCLEROSTIN; MODEL; ALENDRONATE; EXPRESSION; DISEASE; INHIBITION; MICE;

D O I：

10.1002/art.40382

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

引用

页码：157 / 161

页数：5

共 37 条

[1]

Altered Skeletal Expression of Sclerostin and Its Link to Radiographic Progression in Ankylosing Spondylitis [J].

Appel, Heiner ;

Ruiz-Heiland, Gisela ;

Listing, Joachim ;

Zwerina, Jochen ;

Herrmann, Martin ;

Mueller, Ruediger ;

Haibel, Hildrun ;

Baraliakos, Xenofon ;

Hempfing, Axel ;

Rudwaleit, Martin ;

Sieper, Joachim ;

Schett, Georg .

ARTHRITIS AND RHEUMATISM, 2009, 60 (11) :3257-3262

[2]

Loss of sclerostin promotes osteoarthritis in mice via β-catenin-dependent and -independent Wnt pathways [J].

Bouaziz, Wafa ;

Funck-Brentano, Thomas ;

Lin, Hilene ;

Marty, Caroline ;

Ea, Hang-Korng ;

Hay, Eric ;

Cohen-Solal, Martine .

ARTHRITIS RESEARCH & THERAPY, 2015, 17

[3]

OSTEOARTHRITIS IN CYNOMOLGUS MACAQUES - A PRIMATE MODEL OF NATURALLY-OCCURRING DISEASE [J].

CARLSON, CS ;

LOESER, RF ;

JAYO, MJ ;

WEAVER, DS ;

ADAMS, MR ;

JEROME, CP .

JOURNAL OF ORTHOPAEDIC RESEARCH, 1994, 12 (03) :331-339

[4]

Carlson CS, 1996, J BONE MINER RES, V11, P1209

[5]

Increased chondrocyte sclerostin may protect against cartilage degradation in osteoarthritis [J].

Chan, B. Y. ;

Fuller, E. S. ;

Russell, A. K. ;

Smith, S. M. ;

Smith, M. M. ;

Jackson, M. T. ;

Cake, M. A. ;

Read, R. A. ;

Bateman, J. F. ;

Sambrook, P. N. ;

Little, C. B. .

OSTEOARTHRITIS AND CARTILAGE, 2011, 19 (07) :874-885

[6]

A decreased subchondral trabecular bone tissue elastic modulus is associated with pre-arthritic cartilage damage [J].

Day, JS ;

Ding, M ;

van der Linden, JC ;

Hvid, I ;

Sumner, DR ;

Weinans, H .

JOURNAL OF ORTHOPAEDIC RESEARCH, 2001, 19 (05) :914-918

[7]

A LONGITUDINAL-STUDY OF SUBCHONDRAL PLATE AND TRABECULAR BONE IN CRUCIATE-DEFICIENT DOGS WITH OSTEOARTHRITIS FOLLOWED UP FOR 54 MONTHS [J].

DEDRICK, DK ;

GOLDSTEIN, SA ;

BRANDT, KD ;

OCONNOR, BL ;

GOULET, RW ;

ALBRECHT, M .

ARTHRITIS AND RHEUMATISM, 1993, 36 (10) :1460-1467

[8]

Dkk-1-Mediated Inhibition of Wnt Signaling in Bone Ameliorates Osteoarthritis in Mice [J].

Funck-Brentano, Thomas ;

Bouaziz, Wafa ;

Marty, Caroline ;

Geoffroy, Valerie ;

Hay, Eric ;

Cohen-Solal, Martine .

ARTHRITIS & RHEUMATOLOGY, 2014, 66 (11) :3028-3039

[9]

The role of subchondral bone remodeling in osteoarthritis - Reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model [J].

Hayami, T ;

Pickarski, M ;

Wesolowski, GA ;

Mclane, J ;

Bone, A ;

Destefano, J ;

Rodan, GA ;

Duong, LT .

ARTHRITIS AND RHEUMATISM, 2004, 50 (04) :1193-1206

[10]

Neutralisation of Dkk-1 protects from systemic bone loss during inflammation and reduces sclerostin expression [J].

Heiland, Gisela Ruiz ;

Zwerina, Karin ;

Baum, Wolfgang ;

Kireva, Trayana ;

Distler, Joerg H. ;

Grisanti, Mario ;

Asuncion, Frank ;

Li, Xiadong ;

Ominsky, Michael ;

Richards, William ;

Schett, Georg ;

Zwerina, Jochen .

ANNALS OF THE RHEUMATIC DISEASES, 2010, 69 (12) :2152-2159

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