Design of folded peptides

被引：616

作者：

Venkatraman, J

Shankaramma, SC

Balaram, P ^{[1
]}

机构：

[1] Indian Inst Sci, Mol Biophys Unit, Bangalore 560012, Karnataka, India

[2] Jawaharlal Nehru Ctr Adv Sci Res, Chem Biol Unit, Bangalore 560004, Karnataka, India

来源：

CHEMICAL REVIEWS | 2001年 / 101卷 / 10期

关键词：

D O I：

10.1021/cr000053z

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The various techniques used in the design of polypeptide structures were discussed. The assembly of supersecondary structures has largely used solvent forces as the major determinant in formation of compact structures. The expansion of amino acid repertoire by the induction of β-amino acids and higher homologues will help in expanding the diversity of conformationally well-defined peptide structures.

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页码：3131 / 3152

页数：22

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