Human leucocyte antigens in tympanosclerosis

被引:11
作者
Dursun, G
Acar, A
Turgay, M
Calguner, M
机构
[1] ANKARA UNIV, SCH MED, ENT DEPT, TR-06100 ANKARA, TURKEY
[2] ANKARA UNIV, SCH MED, DEPT IMMUNOL, TR-06100 ANKARA, TURKEY
关键词
human leucocyte antigen (HLA); tympanosclerosis;
D O I
10.1046/j.1365-2273.1997.00867.x
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
This study was designed to evaluate the association between certain HLA antigens and tympanosclerosis. The serum concentrations of HLA antigens were measured by a microlymphocytotoxicity technique in patients with tympanosclerosis and compared with a healthy control group. The serum levels of HLA-B35 and -DR3 were significantly higher in the patients with tympanosclerosis. This result suggests that certain types of HLA antigens may play an important role as an indicator or mediator in the pathogenesis of tympanosclerosis.
引用
收藏
页码:62 / 64
页数:3
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