Variation in breastmilk HIV-1 viral load in left and right breasts during the first 3 months of lactation

被引：33

作者：

Willumsen, JF ^{[1
]}

Newell, ML

Filteau, SM

Coutsoudis, A

Dwarika, S

York, D

Tomkins, AM

Coovadia, HM

机构：

[1] Inst Child Hlth, Ctr Int Child Hlth, London, England

[2] Inst Child Hlth, Dept Paediat Epidemiol & Biostat, London, England

[3] Univ KwaZulu Natal, Sch Med, Dept Virol, ZA-4001 Durban, South Africa

[4] Univ KwaZulu Natal, Sch Med, Dept Paediat & Child Hlth, ZA-4001 Durban, South Africa

来源：

AIDS | 2001年 / 15卷 / 14期

关键词：

D O I：

10.1097/00002030-200109280-00026

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The mechanism and risk factors associated with mother-to-child transmission of HIV-1 through breastfeeding remain unclear; breastmilk viral load may be an important determinant of transmission. Analysis of breastmilk cell-free viral load in samples taken from each breast at 1, 6 and 14 weeks postpartum showed that HIV-1 is shed intermittently and load may differ considerably between breasts of an individual woman at any given time. Breastmilk HIV-1 load was undetectable in approximately one-third of samples.

引用

页码：1896 / 1898

页数：3

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