Serum levels of luteinizing and follicle-stimulating hormones in normal and poor-responding patients undergoing ovarian stimulation with urofollitropin after pituitary downregulation

被引：23

作者：

Fridstrom, M ^{[1
]}

Akerlof, E ^{[1
]}

Sjoblom, P ^{[1
]}

Hillensjo, T ^{[1
]}

机构：

[1] HUDDINGE UNIV HOSP, KAROLINSKA INST, DEPT OBSTET & GYNECOL, S-14186 HUDDINGE, SWEDEN

来源：

GYNECOLOGICAL ENDOCRINOLOGY | 1997年 / 11卷 / 01期

关键词：

poor-responders; pituitary suppression; ovulation stimulation; serum gonadotropin levels;

D O I：

10.3109/09513599709152313

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We were interested in the degree of downregulation in women with poor response to in vitro fertilization (IVF) treatment. Ten women who were poor-responders, arbitrarily defined as having fewer than three follicles with diameter > 14 mm on days 9 and 10 of urofollitropin therapy, were compared with ten women who were not poor-responders, in a standard IVF program. The serum levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH) and estradiol after pituitary down-regulation did not differ between the two groups. The daily dose and the serum level of FSH were higher in poor-responders and there was a significant correlation between the dose of urofollitropin and the serum FSH level. There was no difference in serum LH level during ovulation stimulation between the groups. The clinical pregnancy rate was similar in the two groups although fewer embryos were transferred in the poor-response group. In conclusion, there was no difference with regard to pituitary suppression in normal-responders and poor-responders.

引用

页码：25 / 28

页数：4