Comparison of Campylobacter jejuni isolates implicated in Guillain-Barre syndrome and strains that cause enteritis by a DNA microarray

被引：48

作者：

Leonard, EE

Tompkins, LS

Falkow, S

Nachamkin, I

机构：

[1] Univ Penn, Sch Med, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA

[2] Stanford Univ, Div Infect Dis, Stanford, CA 94305 USA

[3] Stanford Univ, Dept Microbiol & Immunol, Stanford, CA 94305 USA

来源：

INFECTION AND IMMUNITY | 2004年 / 72卷 / 02期

关键词：

D O I：

10.1128/IAI.72.2.1199-1203.2004

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We asked whether Campylobacter jejuni isolated from patients with Guillain-Barre syndrome (GBS) differ from isolates isolated from patients with uncomplicated gastrointestinal infection using DNA microarray analysis. We found that specific GBS genes or regions were not identified, and microarray analysis confirmed significant genomic heterogeneity among the isolates.

引用

收藏

页码：1199 / 1203

页数：5

相关论文

共 22 条

[1]

[Anonymous], 1996, ESCHERICHIA COLI SAL, P307

[2] DNA sequence and mutational analyses of the pVir plasmid of Campylobacter jejuni 81-176 [J].

Bacon, DJ ;

Alm, RA ;

Hu, L ;

Hickey, TE ;

Ewing, CP ;

Batchelor, RA ;

Trust, TJ ;

Guerry, P .

INFECTION AND IMMUNITY, 2002, 70 (11) :6242-6250

[3] Involvement of a plasmid in virulence of Campylobacter jejuni 81-176 [J].

Bacon, DJ ;

Alm, RA ;

Burr, DH ;

Hu, L ;

Kopecko, DJ ;

Ewing, CP ;

Trust, TJ ;

Guerry, P .

INFECTION AND IMMUNITY, 2000, 68 (08) :4384-4390

[4] Whole genome comparison of Campylobacter jejuni human isolates using a low-cost microarray reveals extensive genetic diversity [J].

Dorrell, N ;

Mangan, JA ;

Laing, KG ;

Hinds, J ;

Linton, D ;

Al-Ghusein, H ;

Barrell, BG ;

Parkhill, J ;

Stoker, NG ;

Karlyshev, AV ;

Butcher, PD ;

Wren, BW .

GENOME RESEARCH, 2001, 11 (10) :1706-1715

[5] Absence of clonality of Campylobacter jejuni in serotypes other than HS:19 associated with Guillain-Barre syndrome and gastroenteritis [J].

Engberg, J ;

Nachamkin, I ;

Fussing, V ;

McKhann, GM ;

Griffin, JW ;

Piffaretti, JC ;

Nielsen, EM ;

Gerner-Smidt, P .

JOURNAL OF INFECTIOUS DISEASES, 2001, 184 (02) :215-220

[6]

Friedman C.R., 2000, CAMPYLOBACTER, V2nd, P121

[7] Restriction fragment length polymorphism analysis and random amplified polymorphic DNA analysis of Campylobacter jejuni strains isolated from patients with Guillain-Barre syndrome [J].

Fujimoto, S ;

Allos, BM ;

Misawa, N ;

Patton, CM ;

Blaser, MJ .

JOURNAL OF INFECTIOUS DISEASES, 1997, 176 (04) :1105-1108

[8] Acute motor axonal neuropathy: An antibody-mediated attack on axolemma [J].

HaferMacko, C ;

Hsieh, ST ;

Li, CY ;

Ho, TW ;

Sheikh, K ;

Cornblath, DR ;

McKhann, GM ;

Asbury, AK ;

Griffin, JW .

ANNALS OF NEUROLOGY, 1996, 40 (04) :635-644

[9] Immune attack on the Schwann cell surface in acute inflammatory demyelinating polyneuropathy [J].

HaferMacko, CE ;

Sheikh, KA ;

Li, CY ;

Ho, TW ;

Cornblath, DR ;

McKhann, GM ;

Asbury, AK ;

Griffin, JW .

ANNALS OF NEUROLOGY, 1996, 39 (05) :627-637

[10] Human autoimmune neuropathies [J].

Ho, TW ;

McKhann, GM ;

Griffin, JW .

ANNUAL REVIEW OF NEUROSCIENCE, 1998, 21 :187-226