Characterization and management of paradoxical upgrading reactions in HIV-uninfected patients with lymph node tuberculosis

被引：124

作者：

Hawkey, CR

Yap, T

Pereira, J

Moore, DAJ

Davidson, RN

Pasvol, G

Kon, OM

Wall, RA

Wilkinson, RJ

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Wellcome Trust Ctr Res Clin Trop Med, Div Med, Wright Fleming Inst, London W2 1PG, England

[2] Univ Cape Town, Fac Hlth Sci, Inst Infect Dis & Mol Med, ZA-7925 Cape Town, South Africa

[3] Univ London Imperial Coll Sci Technol & Med, St Marys Hosp, Chest & Allergy Clin, London, England

[4] Northwick Pk Hosp & Clin Res Ctr, NW London Hosp Natl Hlth Serv Trust, Dept Infect & Trop Med, Harrow HA1 3UJ, Middx, England

来源：

CLINICAL INFECTIOUS DISEASES | 2005年 / 40卷 / 09期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1086/429317

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

In a retrospective analysis, paradoxical deterioration of lymph node tuberculosis in human immunodeficiency virus uninfected patients was common, occurring in 25 (23%) of 109 patients after treatment had been given for a median of 46 days (interquartile range, 21 - 139 days) and persisting for a median of 67.5 days ( interquartile range, 34 - 111 days). We found no association between the use of steroids and the duration of reaction.

引用

页码：1368 / 1371

页数：4

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