Caspase activation finds fertile ground

被引:8
作者
Baehrecke, EH [1 ]
机构
[1] Univ Maryland, Inst Biotechnol, Ctr Biosyst Res, College Pk, MD 20742 USA
关键词
D O I
10.1016/S1534-5807(03)00134-5
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Cytochrome c is a critical regulator of apoptosome assembly, caspase activation, and programmed cell death. Recent work demonstrates that cytochrome c and caspases function in Drosophila sperm cell differentiation and indicates that caspase activity can be regulated in a subcellular manner in cells that live.
引用
收藏
页码:608 / 609
页数:2
相关论文
共 9 条
  • [1] Caspase activity and a specific cytochrome c are required for sperm differentiation in Drosophila
    Arama, E
    Agapite, J
    Steller, H
    [J]. DEVELOPMENTAL CELL, 2003, 4 (05) : 687 - 697
  • [2] How death shapes life during development
    Baehrecke, EH
    [J]. NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2002, 3 (10) : 779 - 787
  • [3] Apoptosis is physiologically restricted to a specialized cytoplasmic compartment in rat spermatids
    Blanco-Rodríguez, J
    Martínez-García, C
    [J]. BIOLOGY OF REPRODUCTION, 1999, 61 (06) : 1541 - 1547
  • [4] The role of cytochrome c in caspase activation in Drosophila melanogaster cells
    Dorstyn, L
    Read, S
    Cakouros, D
    Huh, JR
    Hay, BA
    Kumar, S
    [J]. JOURNAL OF CELL BIOLOGY, 2002, 156 (06) : 1089 - 1098
  • [5] Programmed cell death in animal development
    Jacobson, MD
    Weil, M
    Raff, MC
    [J]. CELL, 1997, 88 (03) : 347 - 354
  • [6] Dark is a Drosophila homologue of Apaf-1/CED-4 and functions in an evolutionarily conserved death pathway
    Rodriguez, A
    Oliver, H
    Zou, H
    Chen, P
    Wang, XD
    Abrams, JM
    [J]. NATURE CELL BIOLOGY, 1999, 1 (05) : 272 - 279
  • [7] DYNAMICS OF SPERMIOGENESIS IN DROSOPHILA-MELANOGASTER .1. INDIVIDUALIZATION PROCESS
    TOKUYASU, KT
    HARDY, RW
    PEACOCK, WJ
    [J]. ZEITSCHRIFT FUR ZELLFORSCHUNG UND MIKROSKOPISCHE ANATOMIE, 1972, 124 (04): : 479 - &
  • [8] Drosophila Bruce can potently suppress Rpr- and Grim-dependent but not hid-dependent cell death
    Vernooy, SY
    Chow, V
    Su, J
    Verbrugghe, K
    Yang, J
    Cole, S
    Olson, MR
    Hay, BA
    [J]. CURRENT BIOLOGY, 2002, 12 (13) : 1164 - 1168
  • [9] The role of ARK in stress-induced apoptosis in Drosophila cells
    Zimmermann, KC
    Ricci, JE
    Droin, NM
    Green, DR
    [J]. JOURNAL OF CELL BIOLOGY, 2002, 156 (06) : 1077 - 1087