Amino acid nucleic acids: Synthesis and hybridization properties of a novel class of antisense oligonucleotides

被引：23

作者：

Ramasamy, KS

Seifert, W

机构：

[1] ICN Research Department, ICN Pharmaceuticals, Inc., Costa Mesa, CA 92626

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1996年 / 6卷 / 15期

关键词：

D O I：

10.1016/0960-894X(96)00320-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Oligonucleotides containing novel phoshoramidite 12 were synthesized and studied for their hybridization properties for the first time. Interestingly, these modified oligonucleotides showed a remarkable resistance to exonuclease. Copyright (C) 1996 Elsevier Science Ltd

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页码：1799 / 1804

页数：6

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