Structural genomics: keystone for a Human Proteome Project

被引：98

作者：

Montelione, GT ^{[1
]}

Anderson, S

机构：

[1] Rutgers State Univ, Ctr Adv Biotechnol & Med, Piscataway, NJ 08854 USA

[2] Rutgers State Univ, Dept Mol Biol & Biochem, Piscataway, NJ 08854 USA

来源：

NATURE STRUCTURAL BIOLOGY | 1999年 / 6卷 / 01期

关键词：

D O I：

10.1038/4878

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A natural extension of the genome sequencing projects involves analysis of the corresponding three dimensional protein structures. This emerging field of 'structural genomics' has the potential to unify our understanding of the structural basis of protein function.

引用

页码：11 / 12

页数：2

共 9 条

[1] Structural genomics: Bioinformatics in the driver's seat
Gaasterland, T
[J]. NATURE BIOTECHNOLOGY, 1998, 16 (07) : 625 - 627
[2] Phase determination from multiwavelength anomalous diffraction measurements
Hendrickson, WA
Ogata, CM
[J]. MACROMOLECULAR CRYSTALLOGRAPHY, PT A, 1997, 276 : 494 - 523
[3] Shining a light on structural genomics
Kim, SH
[J]. NATURE STRUCTURAL BIOLOGY, 1998, 5 (Suppl 8) : 643 - 645
[4] X-ray crystallography - Taking a structured approach to understanding proteins
Pennisi, E
[J]. SCIENCE, 1998, 279 (5353) : 978 - 979
[5] 100,000 protein structures for the biologist
Andrej Šali
[J]. Nature Structural Biology, 1998, 5 (12) : 1029 - 1032
[6] The Argonne Structural Genomics Workshop: Lamaze class for the birth of a new science
Shapiro, L
Lima, CD
[J]. STRUCTURE, 1998, 6 (03) : 265 - 267
[7] Class-directed structure determination: Foundation for a protein structure initiative
Terwilliger, TC
Waldo, G
Peat, TS
Newman, JM
Chu, K
Berendzen, J
[J]. PROTEIN SCIENCE, 1998, 7 (09) : 1851 - 1856
[8] Lessons learned, promises kept: A biologist's eye view of the genome project
Tilghman, SM
[J]. GENOME RESEARCH, 1996, 6 (09): : 773 - 780
[9] The second decade -: into the third millennium
Wüthrich, K
[J]. NATURE STRUCTURAL BIOLOGY, 1998, 5 (Suppl 7) : 492 - 495

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