Charcot-Marie-Tooth disease type 2 with restless legs syndrome

被引：78

作者：

Gemignani, F ^{[1
]}

Marbini, A ^{[1
]}

Di Giovanni, G ^{[1
]}

Salih, S ^{[1
]}

Terzano, MG ^{[1
]}

机构：

[1] Univ Parma, Ist Neurol, I-43100 Parma, Italy

来源：

NEUROLOGY | 1999年 / 52卷 / 05期

关键词：

D O I：

10.1212/WNL.52.5.1064

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In a series of 44 consecutive patients with Charcot-Marie-Tooth disease (CMT), we found restless legs syndrome (RLS) in 10 of 27 CMT type 2 (CMT2) patients (37%)and in none of 17 CMT type 1 patients (p = 0.004). In the CMT2 patients, RLS was associated with positive sensory symptoms (10/10 versus 10/17; p = 0.026). This finding supports the view that a disorder of sensory input plays a role in the pathogenesis of RLS. Symptomatic treatment may benefit these patients.

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页码：1064 / 1066

页数：3

相关论文

共 11 条

[1] Cerebral generators involved in the pathogenesis of the restless legs syndrome [J].

Bucher, SF ;

Seelos, KC ;

Oertel, WH ;

Reiser, M ;

Trenkwalder, C .

ANNALS OF NEUROLOGY, 1997, 41 (05) :639-645

[2]

Dyck P, 1993, PERIPHERAL NEUROPATH, V1993, P1094

[3] Hereditary motor and sensory neuropathy IIB: Clinical and electrodiagnostic characteristics [J].

Elliott, JL ;

Kwon, JM ;

Goodfellow, PJ ;

Yee, WC .

NEUROLOGY, 1997, 48 (01) :23-28

[4] Cryoglobulinaemic neuropathy manifesting with restless legs syndrome [J].

Gemignani, F ;

Marbini, A ;

DiGiovanni, G ;

Salih, S ;

Margarito, FP ;

Pavesi, G ;

Terzano, MG .

JOURNAL OF THE NEUROLOGICAL SCIENCES, 1997, 152 (02) :218-223

[5] THE CLINICAL-FEATURES OF HEREDITARY MOTOR AND SENSORY NEUROPATHY TYPE-I AND TYPE-II [J].

HARDING, AE ;

THOMAS, PK .

BRAIN, 1980, 103 (JUN) :259-280

[6] EVIDENCE OF PERIPHERAL AXONAL NEUROPATHY IN PRIMARY RESTLESS LEGS SYNDROME [J].

IANNACCONE, S ;

ZUCCONI, M ;

MARCHETTINI, P ;

FERINISTRAMBI, L ;

NEMNI, R ;

QUATTRINI, A ;

PALAZZI, S ;

LACERENZA, M ;

FORMAGLIO, F ;

SMIRNE, S .

MOVEMENT DISORDERS, 1995, 10 (01) :2-9

[7] Restless legs syndrome: Clinicoetiologic correlates [J].

Ondo, W ;

Jankovic, J .

NEUROLOGY, 1996, 47 (06) :1435-1441

[8]

PELLETIER G, 1992, NEUROLOGY, V42, P1663

[9]

Rutkove SB, 1996, MUSCLE NERVE, V19, P670, DOI 10.1002/(SICI)1097-4598(199605)19:5<670::AID-MUS20>3.0.CO

[10]

2-Q