Postural myoclonus induced by phenytoin

被引：13

作者：

Duarte, J ^{[1
]}

Sempere, AP ^{[1
]}

Cabezas, MC ^{[1
]}

Marcos, J ^{[1
]}

Claveria, LE ^{[1
]}

机构：

[1] GEN HOSP SEGOVIA,DEPT INTERNAL MED,SEGOVIA,SPAIN

来源：

CLINICAL NEUROPHARMACOLOGY | 1996年 / 19卷 / 06期

基金：

欧盟地平线“2020”;

关键词：

phenytoin; drug; postural myoclonus; movement disorders;

D O I：

10.1097/00002826-199619060-00009

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Involuntary movements are an infrequent complication of treatment with phenytoin and include tremor, asterixis. myoclonus, parkinsonism, and dyskinesias. The mechanism by which phenytoin exerts its actions is unclear. Phenytoin has been observed to exert variable effects on dopamine metabolites and also may induce changes in serotonergic activity. In this report, we discuss the available experimental evidence concerning the possible mechanisms of involuntary movements induced by phenytoin. We describe a case of postural myoclonus during treatment with phenytoin.

引用

页码：536 / 538

页数：3

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