The Impact of Pharmacogenomics on the Management of Cardiac Disease

被引：13

作者：

Pereira, N. L. ^{[1
]}

Weinshilboum, R. M. ^{[2
]}

机构：

[1] Mayo Clin, Dept Internal Med, Div Cardiovasc Dis, Rochester, MN 55905 USA

[2] Mayo Clin, Div Clin Pharmacol, Dept Mol Pharmacol & Expt Therapeut, Rochester, MN USA

来源：

CLINICAL PHARMACOLOGY & THERAPEUTICS | 2011年 / 90卷 / 04期

关键词：

D O I：

10.1038/clpt.2011.187

中图分类号：

R9 [药学];

学科分类号：

100702 [药剂学];

摘要：

Pharmacogenomics promises to help maximize efficacy and minimize adverse drug reactions. It could have a significant impact on the treatment of cardiovascular disease, the leading cause of death in the United States. The past decade has seen pharmacogenomics move from study of a candidate gene to genome-wide approaches, with the development of a series of pharmacogenetic tests. However, many barriers need to be overcome for cardiovascular pharmacogenomics to have its promised clinical impact.

引用

页码：493 / 495

页数：4

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