Gene regulation: Hacking the network on a sugar high

被引:1
作者
Ellis, Tom [1 ,2 ]
Wang, Xiao [1 ,2 ]
Collins, James J. [1 ,2 ]
机构
[1] Boston Univ, Ctr BioDynam, Boston, MA 02115 USA
[2] Boston Univ, Dept Biomed Engn, Boston, MA 02115 USA
关键词
D O I
10.1016/j.molcel.2008.03.005
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In a recent issue of Molecular Cell, Kaplan et al. (2008) determine the input functions for 19 E coli sugar-utilization genes by using a two-dimensional high-throughput approach. The resulting input-function map reveals that gene network regulation follows non-Boolean, and often nonmonotonic, logic.
引用
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页码:1 / 2
页数:2
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