LC-PUFA content in human milk: Is it always optimal?

被引:12
作者
Agostoni, C [1 ]
机构
[1] Univ Milan, Dept Paediat, San Paolo Hosp, I-20142 Milan, Italy
关键词
human milk; long-chain polyunsaturated fatty acids; maternal diet;
D O I
10.1080/08035250500375491
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
The content of long-chain polyunsaturated fatty acids (LC-PUFAs) in human milk has been connected with infant growth and developmental indices. The LC-PUFA content of human milk usually reflects the dietary habits of mothers, so questions have been raised regarding the possibility of enriching maternal diet with LC-PUFAs during lactation (or even before) in order to improve infant outcome. Nevertheless, environmental and genetic factors have independent roles in affecting both maternal milk composition and infant development. Conclusion: Diet-related differences in the LC-PUFA composition of human milk are under active investigation for their possible contribution to infant development, but environment- and gene-related differences in both human milk composition and maternal diet should be considered in evaluating the adaptive mechanisms of infants and the effects of specific LC-PUFA dietary supplementations.
引用
收藏
页码:1532 / 1534
页数:3
相关论文
共 26 条
[1]   Growth patterns of breast fed and formula fed infants in the first 12 months of life:: an Italian study [J].
Agostoni, C ;
Grandi, F ;
Giannì, ML ;
Silano, M ;
Torcoletti, M ;
Giovannini, M ;
Riva, E .
ARCHIVES OF DISEASE IN CHILDHOOD, 1999, 81 (05) :395-399
[2]   Compliance of present recommendations of fatty acids in formulas for term infants with the actual human milk fatty acid composition in different populations [J].
Agostoni, C .
ACTA PAEDIATRICA, 2003, 92 (07) :785-787
[3]   Breastfeeding duration, milk fat composition and developmental indices at 1 year of life among breastfed infants [J].
Agostoni, C ;
Marangoni, F ;
Lammardo, AM ;
Giovannini, M ;
Riva, E ;
Galli, C .
PROSTAGLANDINS LEUKOTRIENES AND ESSENTIAL FATTY ACIDS, 2001, 64 (02) :105-109
[4]   A randomized controlled trial of early dietary supply of long-chain polyunsaturated fatty acids and mental development in term infants [J].
Birch, EE ;
Garfield, S ;
Hoffman, DR ;
Uauy, R ;
Birch, DG .
DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 2000, 42 (03) :174-181
[5]   ARACHIDONIC-ACID STATUS CORRELATES WITH 1ST YEAR GROWTH IN PRETERM INFANTS [J].
CARLSON, SE ;
WERKMAN, SH ;
PEEPLES, JM ;
COOKE, RJ ;
TOLLEY, EA .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (03) :1073-1077
[6]  
Cetin I, 2002, PEDIATR RES, V52, P750, DOI [10.1203/01.PDR.0000031923.07968.D5, 10.1203/00006450-200211000-00023]
[7]   Growth and development of preterm infants fed infant formulas containing docosahexaenoic acid and arachidonic acid [J].
Clandinin, MT ;
Van Aerde, JE ;
Merkel, KL ;
Harris, CL ;
Springer, MA ;
Hansen, JW ;
Diersen-Schade, DA .
JOURNAL OF PEDIATRICS, 2005, 146 (04) :461-468
[8]   The potential role for arachidonic and docosahexaenoic acids in protection against some central nervous system injuries in preterm infants [J].
Crawford, MA ;
Golfetto, I ;
Ghebremeskel, K ;
Min, Y ;
Moodley, T ;
Poston, L ;
Phylactos, A ;
Cunnane, S ;
Schmidt, W .
LIPIDS, 2003, 38 (04) :303-315
[9]  
FESKENS EJM, 1993, ANN NY ACAD SCI, V683, P9, DOI 10.1111/j.1749-6632.1993.tb35688.x
[10]   Long chain polyunsaturated fatty acid supplementation in infant formula and blood pressure in later childhood: follow up of a randomised controlled trial [J].
Forsyth, JS ;
Willatts, P ;
Agostoni, C ;
Bissenden, J ;
Casaer, P ;
Boehm, G .
BRITISH MEDICAL JOURNAL, 2003, 326 (7396) :953-955