The use of a continuous flow-reactor employing a mixed hydrogen-liquid flow stream for the efficient reduction of imines to amines

被引：119

作者：

Saaby, S ^{[1
]}

Knudsen, KR ^{[1
]}

Ladlow, M ^{[1
]}

Ley, SV ^{[1
]}

机构：

[1] Univ Cambridge, Dept Chem, GlaxoSmithKline, Cambridge CB2 1EW, England

来源：

CHEMICAL COMMUNICATIONS | 2005年 / 23期

关键词：

D O I：

10.1039/b504854k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Imines have been reduced to amines in high yield, and with excellent chemoselectivity, by catalytic hydrogenation in a continuous flow-reactor, utilising an electrochemically-generated hydrogen source to produce a mixed hydrogen liquid flow stream.

引用

页码：2909 / 2911

页数：3

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