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Interaction of viral proteins with host cell death machinery

被引：33
作者：
Granville, DJ
Carthy, CM
Yan, DC
Hunt, DWC
McManus, BM
机构：
[1] Univ British Columbia, St Pauls Hosp, Dept Pathol & Lab Med, Cardiovasc Res Lab, Vancouver, BC V6Z 1Y6, Canada
[2] QLT PhotoTherapeut Inc, Vancouver, BC, Canada
来源：
CELL DEATH AND DIFFERENTIATION | 1998年 / 5卷 / 08期
关键词：
apoptosis; virus; cytopathic effect; viral persistence;
D O I：
10.1038/sj.cdd.4400388
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
In recent years, intense research has been directed towards understanding molecular mechanisms involved in viral pathogenesis. It is now known that many viruses manipulate host defense mechanisms to prevent apoptosis in order to maximize viral replication. Towards the end of their replication cycle, certain viruses direct the synthesis of proteins that induce apoptosis or cell lysis thereby facilitating viral release from the cell. The present review summarizes the current understanding of interactions between viral proteins and the host cell death machinery.
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收藏
页码：653 / 659
页数：7
相关论文
共 86 条
  • [1] Inhibition of caspase proteases by CrmA enhances the resistance of human leukemic cells to multiple chemotherapeutic agents
    Antoku, K
    Liu, Z
    Johnson, DE
    [J]. LEUKEMIA, 1997, 11 (10) : 1665 - 1672
  • [2] POLIOVIRUS 2A(PRO) EXPRESSION INHIBITS GROWTH OF YEAST-CELLS
    BARCO, A
    CARRASCO, L
    [J]. FEBS LETTERS, 1995, 371 (01) : 4 - 8
  • [3] Susceptibility to tumor necrosis factor alpha-induced apoptosis of mouse cells expressing polyomavirus middle and small T antigens
    Bergqvist, A
    Soderbarg, K
    Magnusson, G
    [J]. JOURNAL OF VIROLOGY, 1997, 71 (01) : 276 - 283
  • [4] Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis
    Bertin, J
    Armstrong, RC
    Ottilie, S
    Martin, DA
    Wang, Y
    Banks, S
    Wang, GH
    Senkevich, TG
    Alnemri, ES
    Moss, B
    Lenardo, MJ
    Tomaselli, KJ
    Cohen, JI
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (04) : 1172 - 1176
  • [5] Apoptotic suppression by baculovirus P35 involves cleavage by and inhibition of a virus-induced CED-3/ICE-like protease
    Bertin, J
    Mendrysa, SM
    LaCount, DJ
    Gaur, S
    Krebs, JF
    Armstrong, RC
    Tomaselli, KJ
    Friesen, PD
    [J]. JOURNAL OF VIROLOGY, 1996, 70 (09) : 6251 - 6259
  • [6] NEURONAL CELL KILLING BY THE ENVELOPE PROTEIN OF HIV AND ITS PREVENTION BY VASOACTIVE INTESTINAL PEPTIDE
    BRENNEMAN, DE
    WESTBROOK, GL
    FITZGERALD, SP
    ENNIST, DL
    ELKINS, KL
    RUFF, MR
    PERT, CB
    [J]. NATURE, 1988, 335 (6191) : 639 - 642
  • [7] A RABBITPOX VIRUS SERPIN GENE CONTROLS HOST-RANGE BY INHIBITING APOPTOSIS IN RESTRICTIVE CELLS
    BROOKS, MA
    ALI, AN
    TURNER, PC
    MOYER, RW
    [J]. JOURNAL OF VIROLOGY, 1995, 69 (12) : 7688 - 7698
  • [8] Brown J, 1997, J CELL BIOCHEM, V66, P245, DOI 10.1002/(SICI)1097-4644(19970801)66:2<245::AID-JCB11>3.0.CO
  • [9] 2-G
  • [10] Glycoprotein E-rns of pestiviruses induces apoptosis in lymphocytes of several species
    Bruschke, CJM
    Hulst, MM
    Moormann, RJM
    vanRijn, PA
    vanOirschot, JT
    [J]. JOURNAL OF VIROLOGY, 1997, 71 (09) : 6692 - 6696
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